Definition
US FDA substance register · UNII 5I577UDK52 · registered name 1,10-DECANEDIOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Safety Assessment of Alkane Diols as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name １，１０－デカンジオール: 本品は、次の化学式で表される二価アルコールである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 112-47-0
- EC No.EU chemical inventory number
- 203-975-2
- DTXSIDUS EPA chemical ID
- DTXSID3059420
- DTXCIDUS EPA compound ID
- DTXCID4033261
- IUPAC
- Decane-1,10-diol
- Molecular formula
- C10H22O2
- Molecular weight
- 174.284 g/mol
Measured properties
- Appearance
- Liquid · Solid, [Merck Index] White solid, [Sigma-Aldrich MSDS]
- Colour
- white
- Melting/freezing point
- 72~74 ℃
- Initial boiling point and range
- 192 ℃((20 mmHg))
- Flash point
- 142 ℃
- Vapour pressure
- (8E-5 mmHg (25 C))
- Auto-ignition temperature
- 320 ℃
- Viscosity
- 21.82 cP (72.05 C)
- Molecular weight
- 174.28
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) 1992 - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1981 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1981 according to
Source: US EPA CompTox dashboard
Related literature
- Understanding the Enzymatic Synthesis of a New Biolubricant: Decane-1,10-diyl bis(2-methylpentanoate) · 2024
- Inhibited-nanophase-separation modulated polymerization for recoverable ultrahigh-strain biobased shape memory polymers · 2020
- Diol-Based Polymer Microparticles for Treatment of Cutaneous Aspergillosis in an Immunocompromised Murine Model · 2017
- Composition to ensure protection against microbial pollution of cosmetic products, using mixture of pentylene glycol and Acnacidol BG (butylene glycol (and) 10-hydroxydecanoic acid (and) sebacic acid (and) 1,10-decanediol) at lower dose · 2007
- Crosslinked Poly(Methyl Vinyl Ether-Co-Maleic Anhydride) as Topical Vehicles for Hydrophilic and Lipophilic Drugs · 2003
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese