What is this ingredient?

미국 FDA 물질 등록 · UNII KX6732HE0U · 등록명 1,4-BUTANEDIOL DIMETHACRYLATE · 단일 화학물질

All ingredients

Ingredient Dictionary

1,4-BUTANEDIOL DIMETHACRYLATE

Definition

US FDA substance register · UNII KX6732HE0U · registered name 1,4-BUTANEDIOL DIMETHACRYLATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Leaves a thin film where appliedFILM FORMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ジメタクリル酸１，４－ブタンジオール: 本品は、次の化学式で表される有機化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

1,4-BUTANEDIOL DIMETHACRYLATEINCI2-Propenoic acid, 2-methyl-, 1,4-butanediyl esterSynonymジメタクリル酸１，４－ブタンジオールJapanese labelling name

CAS No.chemical registry number: 2082-81-7
EC No.EU chemical inventory number: 218-218-1
DTXSIDUS EPA chemical ID: DTXSID4044870
DTXCIDUS EPA compound ID: DTXCID2024870

IUPAC: Butane-1,4-diyl bis(2-methylprop-2-enoate)
Molecular formula: C12H18O4
Molecular weight: 226.272 g/mol

Measured properties

Appearance: Liquid, CBI, Wet Solid · Liquid, [HSDB] Colorless liquid, [Aldrich MSDS]
Boiling point: 110 °C @ 3 MM HG
Density: 1.011 @ 25 °C/15.6 °C
Melting/freezing point: 226.28 ℃(EXP)
Initial boiling point and range: 110 ℃(3 mmHg)
Flash point: 139 ℃
Vapour pressure: 0.028 ㎜Hg (at 25℃ EST)
Water solubility: 60 ㎎/ℓ (at 25℃ EST)
Relative density: 1.025 (20℃)
n-Octanol/water partition coefficient (Kow): 3.19 (EST)
Molecular weight: 226.269

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 11 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Monomers6
Photosensitive agent2
Intermediate2
Film former1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 2 eye studies are on record.

Classed as moderate1Classed as low2

The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Sh
Skin Sensitization · Authoritative
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, skin toxicity according to Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.41 equivalent or similar to
Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) individual approach (adopted 22 July 2010) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) dated May 30, 2008
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: The test was performed according to Magnusson B and Kligman AM (1970) in: Allergic Contact Dermatitis in the Guinea Pig. Thomas, Springfield, III
Category 6.3A (Category 2)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Appraisal of the safety of chemicals in foods, druge and cosmetics, by the Staft of the Division of Pharmacology, US FDA, Bewertung von Augen-Lasionen nach Draize (1959) according to other guideline: US FHSA Federal regulation: 16 CFR 1500.42 equivalent or similar to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Category 6.4A (Category 2A)
Eye Irritation · Read Across