Pentane-1,5-diol is a primary alcohol.
Definition
Pentane-1,5-diol is a primary alcohol.
Source: PubChem
US FDA substance register · UNII 07UXZ0SCST · registered name 1,5-Pentanediol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Safety Assessment of Alkane Diols as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 1,5-ペンタンジオール: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 111-29-5
- EC No.EU chemical inventory number
- 203-854-4
- DTXSIDUS EPA chemical ID
- DTXSID2041256
- DTXCIDUS EPA compound ID
- DTXCID0021256
- IUPAC
- Pentane-1,5-diol
- Molecular formula
- C5H12O2
- Molecular weight
- 104.149 g/mol
Measured properties
- Appearance
- CBI, Liquid · Viscous liquid, [Merck Index] Colorless viscous liquid, Hygroscopic, [Alfa Aesar MSDS]
- Boiling point
- 240 °C · 239 °C @760 [mm Hg]
- Melting point
- -18 °C
- Solubility
- Miscible with water · Soluble in water
- Density
- 0.9941 g/cm cu at 20 °C, 0.9858 g/cm cu at 25 °C · 0.994 @ 20°C
- Stability
- Stable under recommended storage conditions.
- Viscosity
- 128 mPa.s at 20 °C · 122.80 cP (20.25 C)
- Colour
- colourless
- pH
- 7.5 ((25 ℃))
- Melting/freezing point
- -18~-15 ℃
- Initial boiling point and range
- 238~242 ℃
- Flash point
- 135 ℃
- Upper/lower flammability or explosive limits
- 13.2 / 1.4 %
- Vapour pressure
- 0.0039 ㎜Hg ((25 ℃))
- Vapour density
- 3.59
- Relative density
- 0.9925-0.9941
- n-Octanol/water partition coefficient (Kow)
- 0.27
- Auto-ignition temperature
- 334 ℃
- Molecular weight
- 104.15
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 17 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Solvent10
- Softener and conditioner4
- Intermediate1
- Humectant1
- Diluent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Register 38 No 187 s 1500.41 ( Haut) und s 1500.42 (Auge), S. 27019 vom 27.09.73 . according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 38 No 187 s 1500.41 ( Haut) und s 1500.42 (Auge), S. 27019 vom 27.09.73 . according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Combining computer-aided enzyme design and chromosomal integration for plasmid-free biosynthesis of 1,5-pentanediol in Escherichia coli · 2026
- Rigid–flexible bio‑based PMBD copolyesters with diol‑length‑controlled thermomechanics and biodegradation for potential humanoid‑skin applications · 2026
- Combining polyesters of citric and azelaic acids to obtain potential topical application biomaterials with antimicrobial activity · 2025
- Insights into the structure of sunscreen lotions: a small-angle neutron scattering study · 2021
- Safety Assessment and Biological Effects of a New Cold Processed SilEmulsion for Dermatological Purpose · 2013
Linked databases 21
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
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