Is there safety information?

자극 및 알러지 가능성 있으나 피부 안전성 높음(민감성 피부도 사용 가능). 미백 기능 때문에 자외선 차단 필요

Are there usage precautions?

피부 밝기 개선, 멜라닌 생합성 억제(미백)수분 유지·장벽 강화 노화방지 및 피부 재생 촉진 (추천 피부타입: 모든피부타입)

All ingredients

Ingredient Dictionary

1-METHYLHYDANTOIN-2-IMIDE

Creatinine is a lactam obtained by formal cyclocondensation of creatine.

How much products actually contain

No product states its amount yet.

Of the products containing it, 5 list it before the 1% line and 23 after it (usually 1% or less).

Products using this ingredient

12 of 28 confirmed · likeliest to carry enough first · See all 28

Definition

Creatinine is a lactam obtained by formal cyclocondensation of creatine. It is a metabolite of creatine. It has a role as a diagnostic agent and a human metabolite. It is a lactam and an imidazolidinone. It is functionally related to a creatine.

Source: PubChem

US FDA substance register · UNII AYI8EX34EU · registered name CREATININE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name １－メチルヒダントイン－２－イミド: 本品は、次の化学式で表されるイミダゾリン誘導体である。

Source: JCIA labelling names (Japan)

Names & identifiers

1-METHYLHYDANTOIN-2-IMIDEINCI1-메틸하이단토인-2-이미드Korean label name (MFDS standard)4H-Imidazol-4-one, 2-amino-1,5-dihydro-1-methyl-Synonym１－メチルヒダントイン－２－イミドJapanese labelling name

CAS No.chemical registry number: 60-27-5
EC No.EU chemical inventory number: 200-466-7
DTXSIDUS EPA chemical ID: DTXSID8045987
DTXCIDUS EPA compound ID: DTXCID6025987

IUPAC: 2-Imino-1-methylimidazolidin-4-one
Molecular formula: C4H7N3O
Molecular weight: 113.12 g/mol

Measured properties

Appearance: solid
Colour: colourless
Flammability (solid, gas): combustible
Vapour pressure: 0.000217 ㎜Hg (@ 25 ℃, est.)
Water solubility: 80100 ㎎/ℓ (@ 16 ℃)
Vapour density: 3.9
Relative density: 1.39 (@ 20.3 ℃)
n-Octanol/water partition coefficient (Kow): -1.76
Auto-ignition temperature: 360 ℃
Decomposition temperature: 300 ℃
Molecular weight: 113.12

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
SkinSens1
Skin Sensitization · QSAR Predicted
Category 6.3A (Category 2)
Skin Irritation · Read Across
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across