Gloshell
Ingredientes

Diccionario de ingredientes

1-NAPHTHOL

1-naphthol is a naphthol carrying a hydroxy group at position 1.

Estructura molecular

Definición

1-naphthol is a naphthol carrying a hydroxy group at position 1. It has a role as a genotoxin and a human xenobiotic metabolite.

Fuente: PubChem

Registro de sustancias de la FDA (EE. UU.) · UNII 2A71EAQ389 · nombre registrado 1-Naphthol · sustancia química única

Fuente: Identificador único de ingredientes de la FDA (UNII)

Funciones cosméticas

Tiñe el cabelloHAIR DYEING

Referencias de seguridad y regulación

Prohibido
Corea del Sur
Restringido o prohibido
Corea del Sur · Taiwán
Restringido
Reino Unido · Taiwán

Fuente: Información regulatoria cosmética del MFDS (Corea) · Directiva cosmética de la ASEAN · Reglamento de cosméticos de la UE · Lista de ingredientes restringidos de Health Canada · Ingredientes cosméticos de la FDA de Taiwán · Normativa cosmética de la FDA de Taiwán · Normativa cosmética del Reino Unido (OPSS)

Argentina · Brasil

  • Field of application and/or use : Oxidation dye for coloring hairs
  • Maximum concentration permitted at final product : 2%
  • Other limitations and requirements : In combination with hydrogen peroxide the maximum concentration in the product ready to use is 1%
  • Use conditions and warnings that must appear on the label : May cause allergic reaction

Canadá

  • Conditions of Use by product type : (a) In Hair dyes as an oxidizing colouring agent (b) In combination with hydrogen peroxide
  • Maximum Concentration Permitted : (a) 2% (b) 1%

ASEAN

  • Field of application and/or use : Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
  • Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0%. The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past

China

  • Concentración máxima : 1%

Unión Europea

  • Product Type, body parts : Hair dye substance in oxidative hair dye products
  • Other : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1 % calculated as free base
  • Wording of conditions of use and warnings : Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past

Unión Europea

  • Product Type, body parts : Hair dye substance in oxidative hair dye products
  • Other : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2,0%
  • Wording of conditions of use and warnings : To be printed on the label: Hair colorants can cause severe allergic reactions.

Fuente: Información regulatoria cosmética del MFDS (Corea)

Sin clasificación en la lista GHS de sustancias tóxicas de Corea · sustancia química existente

Fuente: Registro GHS de sustancias tóxicas de Corea (NIER)

Reglamento de cosméticos de la UE, anexo III (sustancias restringidas), entrada 16 · se aplica a Hair dye substance in oxidative hair dye products

Fuente: Sustancias restringidas UE (anexo III)

Restriction III/16 · Other restriction: ban substances that deplete the ozone layer

Fuente: Lista de ingredientes CosIng (UE)

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2007-2010

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Reviewed by CIR: Final Report on the Safety Assessment of 1-Naphthol

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Más datos: nombres, identificadores, propiedades, ensayos y literatura

Nombres e identificadores

1-NAPHTHOLINCI1-나프톨Nombre en etiquetas coreanas (estándar MFDS)1-NaphthalenolSinónimo1- NAPHTHALENOLSinónimo1-NAPHTHOL, AND ITS SALTSSinónimo
CAS No.número de registro químico
90-15-3
EC No.número de inventario químico de la UE
201-969-4
DTXSIDidentificador químico de la EPA (EE. UU.)
DTXSID6021793
DTXCIDidentificador de compuesto de la EPA (EE. UU.)
DTXCID401793
IUPAC
Naphthalen-1-ol
Fórmula molecular
C10H8O
Peso molecular
144.173 g/mol

Propiedades medidas

Aspecto
Large Crystals · Colorless or yellow solid, [Hawley] Darkens on exposure to light, [Merck Index] Colorless crystalline solid, [MSDSonline]
Olor
Phenolic odor
Punto de ebullición
288 °C · 279.00 to 280.00 °C. @ 760.00 mm Hg
Punto de fusión
96 °C · 94.00 to 95.00 °C. @ 760.00 mm Hg
Solubilidad
In water, 866 mg/L at 25 °C · Very soluble in ethanol and ether, soluble in acetone
Densidad
1.0954 at 98.7 °C/4 °C · 1.0989 @ 99°C
Estabilidad
Water stability: stable at pH < or =6.5, increased transformation with increased pH. /from table/ · Darkens on exposure to air or light.
Constante de disociación
pKa = 9.34 at 25 °C
Punto de fusión/congelación
96 ℃
Punto inicial e intervalo de ebullición
288 ℃
Punto de inflamación
125 ℃
Límites superior/inferior de inflamabilidad o explosividad
5.0 / 0.8 %
Presión de vapor
1.7 ㎜Hg (110℃)
Solubilidad en agua
866 ㎎/ℓ (25℃)
Densidad relativa
1.0954 (98.7℃/ 4℃)
Coeficiente de reparto n-octanol/agua (Kow)
2.85
Temperatura de autoignición
510 ℃
Peso molecular
144.17

Valores medidos en la sustancia en sí. Los datos de KOSHA son una referencia para redactar y revisar fichas de seguridad, no una especificación de una materia prima comercial.

Fuente: PubChem · Fichas de datos de seguridad de KOSHA (Corea)

Para qué lo usan los productos

Usos de los 8 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.

  • Degradant/impurity (EPA)3
  • Dye3
  • Intermediate2

Fuente: Panel CompTox de la EPA

Estudios de irritación y sensibilización

Constan 8 estudios en piel y 6 en ojos.

Clasificado como moderado1

Las conclusiones de los estudios coinciden en general (100%). Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.

Ver los 14 estudios
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Skin irritation - category 2
    Skin Irritation · Screening
  • Category 1
    Skin Irritation · Screening
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Skin corrosion/irritation - Category 2
    Skin Irritation · Screening
  • Classification not possible
    Skin Sensitization · Screening
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • Eye Dam. 1
    Eye Irritation · Authoritative
  • Eye damage - category 1
    Eye Irritation · Screening
  • Corrosive or Irritation Persists for &gt; 21 days
    eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) according to
  • Category 1
    Eye Irritation · Screening
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Serious eye damage/eye irritation - Category 1
    Eye Irritation · Screening

Fuente: Panel CompTox de la EPA

Literatura relacionada

Bases de datos vinculadas 29