2,3-Dicresol is a hydroxytoluene.
Definition
2,3-Dicresol is a hydroxytoluene.
Source: PubChem
US FDA substance register · UNII RLF9YS3586 · registered name 2,3-DIMETHYLPHENOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Korea’s toxic-substance GHS classification: Danger · H411 (category 2) · H301 (category 3) · H311 (category 3) · +1 more
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 526-75-0
- EC No.EU chemical inventory number
- 208-395-3
- DTXSIDUS EPA chemical ID
- DTXSID6025143
- DTXCIDUS EPA compound ID
- DTXCID105143
- IUPAC
- 2,3-Dimethylphenol
- Molecular formula
- C8H10O
- Molecular weight
- 122.167 g/mol
Measured properties
- Appearance
- 2,3-dimethylphenol appears as colorless crystalline solid or brown chunky solid. Taste threshold concentration 0.03 mg/L. Odor threshold concentration 0.5 mg/L. (NTP, 1992) · Liquid
- Odour
- Sweet tarry odor
- Boiling point
- 424 °F at 760 mmHg (NTP, 1992) · 203-225 °C
- Melting point
- 167 °F (NTP, 1992) · 20-76 °C
- Solubility
- less than 1 mg/mL at 73 °F (NTP, 1992) · Freely sol in alcohol, chloroform, ether, benzene, sol in sodium hydroxide soln, slightly sol in water.
- Density
- White, crystalline solid, Specific gravity: 1.02-1.03 @ 15 °C · Saturated liquid density= 63.180 lb/cu ft at 70 °F
- Viscosity
- 1.845 centipoise at 160 °F · 1.85 cP((71℃) )
- Dissociation constant
- pKa= 10.2-10.6 · pKa= 10.54 at 25 °C
- pH
- 10.544
- Melting/freezing point
- 72.8 ℃
- Initial boiling point and range
- 216.9 ℃
- Flash point
- 91 ℃
- Vapour pressure
- 3.24 ㎩
- Water solubility
- 4570 ㎎/ℓ
- Vapour density
- 4.23
- Relative density
- 0.965
- n-Octanol/water partition coefficient (Kow)
- 2.48
- Auto-ignition temperature
- 599 ℃
- Molecular weight
- 149.015
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Cleaning agent2
- Solvent2
- Fragrance2
- Flavouring and nutrient1
- Corrosion inhibitor1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 10 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Classification not possible
Skin Irritation · Screening - Skin Corr. 1B
Skin Irritation · Authoritative - Severe Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to other guideline: As mentioned below - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: As mentioned below - Classification not possible
Skin Sensitization · Screening - Classification not possible
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 15
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Chinese