How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 8 after it (usually 1% or less).
Products using this ingredient
8 of 8 confirmed · likeliest to carry enough first
MiseensceneNew Hello Cream Hair Dye
MiseensceneHello Cream Double Cover 120g Hair Dye (Mystic Black + 5 Other Shades)
MiseensceneAll New Easy & Quick Bubble Hair Dye (Gray Coverage)
MiseensceneAll New Easy & Quick Cream Hair Dye (Gray Coverage/Root Touch-Up)
DASHUDASHU Color Fast Change Hair Dye 120g (3 Types)
MOREMO KeratinLow-Damage Hair Color Matte Deep Brown
MOREMO KeratinMoremo Keratin Low-Damage Hair Color Gray Coverage & Fashion Color 2 Types
MOREMO KeratinLow-Damage Hair Color Ash Gray
Definition
US FDA substance register · UNII Z5Y843J6KQ · registered name 2,4-DIAMINOPHENOXYETHANOL HYDROCHLORIDE · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- South Korea
- Restricted or banned
- South Korea · Taiwan
- Restricted
- Taiwan · United Kingdom
Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)
ASEAN
- Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
- Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 % (as hydrochloride) The direction for use “wear suitable gloves” must be included in label or leaflet text.
- Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows
China
- Maximum concentration : 2%
European Union
- Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
- Other : For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (as hydrochloride) (b) For professional use only.
- Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.†(b) To be printed on the label: The mixing ratio.“For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.â€
Source: MFDS (Korea) cosmetic regulatory information
Restriction III/242
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report: Amended Safety Assessment of 2,4-Diaminophenoxyethanol HCl and 2,4-Diaminophenoxyethanol Sulfate as Used in Cosmetics
Reviewed by CIR: Final Amended Report on the Safety Assessment of 2,4-Diaminophenoxyethanol HCl and 2,4-Diaminophenoxyethanol Sulfate
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 66422-95-5
- EC No.EU chemical inventory number
- 266-357-1
- DTXSIDUS EPA chemical ID
- DTXSID3070462
- DTXCIDUS EPA compound ID
- DTXCID0044812
- IUPAC
- 2-(2,4-Diaminophenoxy)ethan-1-ol--hydrogen chloride (1/2)
- Molecular formula
- C8H14Cl2N2O2
- Molecular weight
- 241.11 g/mol
Measured properties
- Appearance
- Solid, [MSDSonline] Light grey to light pink solid, [EC]
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye3
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 33%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - High Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 20
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- PubChem
- Taiwan FDA cosmetic ingredients
- Taiwan FDA cosmetic regulations
- Tlooto literature search
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata