Gloshell
成分词典

成分词典

2,4-DIAMINOPHENOXYETHANOL HCL

分子结构

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中,0 款将其列在 1% 线之前,8 款列在之后(通常不超过 1%)。

含有此成分的产品

已确认 8 款中的 8 款 · 按含量充足程度排序

定义

美国FDA 物质登记 · UNII Z5Y843J6KQ · 登记名称 2,4-DIAMINOPHENOXYETHANOL HYDROCHLORIDE · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

化妆品中的作用

染发HAIR DYEING

安全与法规参考

禁用
韩国
限用·禁用
韩国
限用
英国

来源: 韩国食药处 化妆品法规信息 · 东盟化妆品指令 · 欧盟化妆品法规 · 台湾FDA 化妆品成分 · 台湾FDA 化妆品法规 · 英国化妆品法规

东盟

  • Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
  • Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.0 % (as hydrochloride) The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : 氧化性染髮產 : 2% (以 hydrochloride 計)

中国

  • 最大配合量 : 2%

欧盟

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
  • Other : For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyelashes must not exceed 2,0 % (as hydrochloride) (b) For professional use only.
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.” (b) To be printed on the label: The mixing ratio.“For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.”

来源: 韩国食药处 化妆品法规信息

Restriction III/242

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Final Report: Amended Safety Assessment of 2,4-Diaminophenoxyethanol HCl and 2,4-Diaminophenoxyethanol Sulfate as Used in Cosmetics

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Amended Report on the Safety Assessment of 2,4-Diaminophenoxyethanol HCl and 2,4-Diaminophenoxyethanol Sulfate

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

2,4-DIAMINOPHENOXYETHANOL HCLINCI염산2,4-디아미노페녹시에탄올韩国标示名称(食药处标准名)Ethanol, 2-(2,4-diaminophenoxy)-, dihydrochloride同义名
CAS No.化学物质登记号
66422-95-5
EC No.欧盟化学品目录编号
266-357-1
DTXSID美国EPA化学品编号
DTXSID3070462
DTXCID美国EPA化合物编号
DTXCID0044812
IUPAC
2-(2,4-Diaminophenoxy)ethan-1-ol--hydrogen chloride (1/2)
分子式
C8H14Cl2N2O2
分子量
241.11 g/mol

实测物性

性状
Solid, [MSDSonline] Light grey to light pink solid, [EC]

这是对物质本身测得的数值,并非原料商品的规格。

来源: PubChem

产品实际使用的用途

这是向美国 EPA 申报含该成分的 3 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Dye3

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 3 项、眼部试验 2 项。

归类为刺激性高1 项归类为低2 项

各项试验结论不一(最多的结论占 33%),因此不能断定该成分有刺激性。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 5 项试验
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

来源: 美国EPA CompTox

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