Ingredient Dictionary

2,4-XYLENOL

2,4-xylenol is a member of the class of phenols that phenol substituted by methyl groups at positions 2 and 4.

Definition

2,4-xylenol is a member of the class of phenols that phenol substituted by methyl groups at positions 2 and 4. It has a role as a volatile oil component and a disinfectant. It is a member of phenols and an aromatic fungicide. It derives from a hydride of a m-xylene.

Source: PubChem

US FDA substance register · UNII 5OD803C081 · registered name 2,4-Dimethylphenol · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Korea’s toxic-substance GHS classification: Danger · H411 (category 2) · H314 (category 1) · H311 (category 3) · +2 more

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

2,4-XYLENOLINCIPhenol, 2,4-dimethyl-Synonym

CAS No.chemical registry number: 105-67-9
EC No.EU chemical inventory number: 203-321-6
DTXSIDUS EPA chemical ID: DTXSID2021864
DTXCIDUS EPA compound ID: DTXCID101864

IUPAC: 2,4-Dimethylphenol
Molecular formula: C8H10O
Molecular weight: 122.167 g/mol

Measured properties

Appearance: solid
Colour: colourless
Melting/freezing point: 25.4~26 ℃
Initial boiling point and range: 211.5 ℃(at 766 mmHg)
Flash point: 80~95 ℃
Upper/lower flammability or explosive limits: 6.4 / 1.1 %
Vapour pressure: 0.102 ㎜Hg (at 20 C)
Water solubility: 5000 ㎎/ℓ
Relative density: 0.9650 (g/cm3 at 20 C)
n-Octanol/water partition coefficient (Kow): 2.3
Auto-ignition temperature: 599 ℃
Molecular weight: 122.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance3
Cleaning agent2
Intermediate2
Solvent2
Corrosion inhibitor1
Catalyst1
No specific technical function1
Elasticizer1

1 other uses

Flavouring and nutrient1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 2 eye studies are on record.

Classed as highly irritating1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Skin Corr. 1B
Skin Irritation · Authoritative
Category 1
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Category 8.2C (Category 1C)
Skin Irritation · Read Across
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)
Category 1
Eye Irritation · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across