- Korean limit
- 0.15%
Definition
US FDA substance register · UNII K89AB8CKG6 · registered name 2,6-Diaminopyridine · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted
- South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)
ASEAN
- Field of application and/or use : Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
- Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0.15 % The direction for use “wear suitable gloves” must be included in label or leaflet text. The direction for use “wear suitable gloves” must be included in label or leaflet text.
- Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows
China
- Maximum concentration : 0.15%
European Union
- Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
- Other : For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 0,15 % (b) For professional use only.
- Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair,— you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.†b) To be printed on the label: The mixing ratio. “For professional use only. This product can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase the risk of allergy. Eyelashes shall not be coloured if the consumer: — has a rash on the face or sensitive, irritated and damaged scalp, — has experienced any reaction after colouring hair or eyelashes, — has experienced a reaction to a temporary ‘black henna’ tattoo in the past. Rinse eyes immediately if product comes into contact with them.†’
Source: MFDS (Korea) cosmetic regulatory information
EU Cosmetics Regulation, Annex III (restricted substances), entry 285 · applies to (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 141-86-6
- EC No.EU chemical inventory number
- 205-507-2
- DTXSIDUS EPA chemical ID
- DTXSID0040127
- DTXCIDUS EPA compound ID
- DTXCID8020127
- IUPAC
- Pyridine-2,6-diamine
- Molecular formula
- C5H7N3
- Molecular weight
- 109.132 g/mol
Measured properties
- Appearance
- Slightly brown solid, [EC: SCCS - Opinion] Light brown, yellow, or off-white powder or flakes, [Alfa Aesar MSDS]
- Boiling point
- 285 °C @760 [mm Hg]
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- SkinSens1
Skin Sensitization · QSAR Predicted - Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 23
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU restricted substances (Annex III)
- EU SCCS safety opinions
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- NIST Chemistry WebBook
- PubChem
- Taiwan FDA cosmetic ingredients
- Taiwan FDA cosmetic regulations
- Tlooto literature search 2
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Chinese