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成分词典

成分词典

2-AMINO-3-HYDROXYPYRIDINE

2-amino-3-hydroxypyridine is a monohydroxypyridine and an aminopyridine.

韩国限量
1.0%
分子结构

定义

美国FDA 物质登记 · UNII P8740PEW4B · 登记名称 2-Amino-3-hydroxypyridine · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

2-amino-3-hydroxypyridine is a monohydroxypyridine and an aminopyridine.

来源: PubChem

化妆品中的作用

染发HAIR DYEING

安全与法规参考

限用
韩国 · 英国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 韩国食药处 化妆品法规信息 · 台湾FDA 化妆品成分 · 台湾FDA 化妆品法规 · 英国化妆品法规

东盟

  • Field of application and/or use : Hair dye substance in oxidative hair dye products. Use for dyeing eyelashes and eyebrows is not permitted.
  • Other limitations and requirements : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0% The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past Do not use to dye eyelashes or eyebrows

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : 氧化性染髮產品 : 1%

中国

  • 最大配合量 : 0.3%

欧盟

  • Product Type, body parts : Hair dye substance in oxidative hair dye products
  • Other : After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1,0%
  • Wording of conditions of use and warnings : To be printed on the label: The mixing ratio. ‘ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.’

来源: 韩国食药处 化妆品法规信息

欧盟化妆品法规 附录III(限用物质) 第211项 · 适用 (a) Hair dye sub­stance in oxidat­ive hair dye products (b) Products in­tended for col­ouring eyelashes

来源: 欧盟限用成分(附录III)

Restriction Annex III/211 - Directive 2012/21/EU · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on 2-Amino-3-hydroxypyridine

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Safety Assessment of 2-Amino-3-Hydroxypyridine as Used in Cosmetics

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

2-AMINO-3-HYDROXYPYRIDINEINCI2-아미노-3-히드록시피리딘韩国标示名称(食药处标准名)3-Pyridinol, 2-amino-同义名
CAS No.化学物质登记号
16867-03-1
EC No.欧盟化学品目录编号
240-886-8
DTXSID美国EPA化学品编号
DTXSID50168588
DTXCID美国EPA化合物编号
DTXCID4091079
IUPAC
2-Aminopyridin-3-ol
分子式
C5H6N2O
分子量
110.116 g/mol

产品实际使用的用途

这是向美国 EPA 申报含该成分的 3 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Dye3

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 3 项、眼部试验 1 项。

归类为低2 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 4 项试验
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across

来源: 美国EPA CompTox

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