Ingredient Dictionary

2-METHYLPROPANAL

Isobutyraldehyde is a member of the class of propanals that is propanal substituted by a methyl group at position 2.

Definition

Isobutyraldehyde is a member of the class of propanals that is propanal substituted by a methyl group at position 2. It has a role as a Saccharomyces cerevisiae metabolite. It is a member of propanals and a 2-methyl-branched fatty aldehyde.

Source: PubChem

US FDA substance register · UNII C42E28168L · registered name Isobutyraldehyde · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Cares for nailsNAIL CONDITIONINGGives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

2-METHYLPROPANALINCI2-메틸프로판알Korean label name (MFDS standard)Propanal, 2-methyl-Synonym

CAS No.chemical registry number: 78-84-2
EC No.EU chemical inventory number: 201-149-6
DTXSIDUS EPA chemical ID: DTXSID9021635
DTXCIDUS EPA compound ID: DTXCID201635

IUPAC: 2-Methylpropanal
Molecular formula: C4H8O
Molecular weight: 72.107 g/mol

Measured properties

Appearance: liquid
Colour: colourless
Melting/freezing point: -65 ℃
Initial boiling point and range: 63~64 ℃
Flash point: -25 ℃
Upper/lower flammability or explosive limits: 10.6 / 1.6 %
Vapour pressure: (15.3 kPa at 20°C)
Water solubility: 6.7 g/100㎖ ( at 20°C)
Vapour density: 2.5
Relative density: 0.8
n-Octanol/water partition coefficient (Kow): 1.2
Auto-ignition temperature: 196 ℃
Molecular weight: 72.12

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 12 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance3
Intermediate3
Flavouring and nutrient2
Hardener2
No specific technical function1
Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 3 eye studies are on record.

Classed as low4

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 8 studies

Not classified
Skin Sensitization · Screening
Category 6.3B (Category 3)
Skin Irritation · Read Across
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Mouse Ear Swelling Test (MEST)
Not classified
Skin Irritation · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Classification not possible
Eye Irritation · Screening
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to