Definition
US FDA substance register · UNII Y9VVU7G7J4 · registered name 2-tert-Butyl-4-methylphenol · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 2409-55-4
- EC No.EU chemical inventory number
- 219-314-6
- DTXSIDUS EPA chemical ID
- DTXSID2020212
- DTXCIDUS EPA compound ID
- DTXCID00212
- IUPAC
- 2-tert-Butyl-4-methylphenol
- Molecular formula
- C11H16O
- Molecular weight
- 164.248 g/mol
Measured properties
- Appearance
- Solid
- Melting/freezing point
- 51.5 ℃( EXP)
- Initial boiling point and range
- 237 ℃( EXP)
- Flash point
- 105 ℃(C.C)
- Vapour pressure
- 0.025 ㎜Hg (at 25℃(extrapolated))
- Water solubility
- 184 ㎎/ℓ (at 25℃(EST))
- Vapour density
- 5.7 ()
- Relative density
- 0.924 (at 20℃)
- n-Octanol/water partition coefficient (Kow)
- 3.97 (EST)
- Molecular weight
- 164.27
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance2
- Antioxidant1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Corrosive
skin irritation: in vivo · Screening · other guideline: Code of Federal Regulations, title 16, section 1500.41 according to - Classification not possible
Skin Sensitization · Screening - Category 6.3A (Category 2)
Skin Irritation · Read Across - SkinIrr2
Skin Irritation · QSAR Predicted - Category 2
Skin Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2A
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Code of Federal Regulation, title 16, section 1500.42 according to
Source: US EPA CompTox dashboard
Linked databases 12
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata