3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group.
Definition
3-tert-butyl-4-hydroxyanisole is an aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group. It has a role as an antioxidant and a human xenobiotic metabolite. It is a member of phenols and an aromatic ether.
Source: PubChem
US FDA substance register · UNII 62RAC24292 · registered name 3-TERT-BUTYL-4-HYDROXYANISOLE · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 121-00-6
- EC No.EU chemical inventory number
- 204-442-7
- DTXSIDUS EPA chemical ID
- DTXSID7040788
- DTXCIDUS EPA compound ID
- DTXCID90215
- IUPAC
- 2-tert-Butyl-4-methoxyphenol
- Molecular formula
- C11H16O2
- Molecular weight
- 180.247 g/mol
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance2
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 1 eye studies are on record.
The study conclusions largely agree (80%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 7 studies
- SkinSens1
Skin Sensitization · QSAR Predicted - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Category 6.5B (Category 1)
Skin Sensitization · Read Across - SkinIrr2
Skin Irritation · QSAR Predicted - Moderate or Mild Irritation
eye irritation: in vivo · Screening · other guideline: according to
Source: US EPA CompTox dashboard