3-hydroxypropionic acid is a 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group.
Definition
3-hydroxypropionic acid is a 3-hydroxy monocarboxylic acid that is propionic acid in which one of the hydrogens attached to the terminal carbon is replaced by a hydroxy group. It has a role as an Escherichia coli metabolite and a human metabolite. It is an omega-hydroxy-short-chain fatty acid and a 3-hydroxy monocarboxylic acid. It is functionally related to a propionic acid. It is a conjugate acid of a 3-hydroxypropionate.
Source: PubChem
US FDA substance register · UNII C4ZF6XLD2X · registered name HYDRACRYLIC ACID · single chemical substance
3-Hydroxypropionic Acid is the organic acid that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 503-66-2
- EC No.EU chemical inventory number
- 207-974-8
- DTXSIDUS EPA chemical ID
- DTXSID50198305
- DTXCIDUS EPA compound ID
- DTXCID40120796
- IUPAC
- 3-Hydroxypropanoic acid
- Molecular formula
- C3H6O3
- Molecular weight
- 90.078 g/mol
Measured properties
- Appearance
- liquid
- Melting/freezing point
- &, lt, 25 ℃
- Initial boiling point and range
- 222.07 ℃
- Flash point
- 137 ℃
- Vapour pressure
- 0.0191 ㎜Hg
- Water solubility
- 1000000 ㎎/ℓ
- Relative density
- 1.283
- n-Octanol/water partition coefficient (Kow)
- -0.89
- Molecular weight
- 90.078
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
Related literature
- Experiments on the Carcinogenicity and Reactivity of β-propiolactone · 1961
- Comprehensive analysis of differences in cashmere production performance in Liaoning cashmere goats by using metabolomics and transcriptomics · 2025
- Bioproduction of 3-Hydroxypropionic Acid by Enhancing the Precursor Supply with a Hybrid Pathway and Cofactor Regeneration. · 2024
- Improvement of 3-Hydroxypropionic Acid Tolerance in Klebsiella pneumoniae by Novel Transporter YohJK. · 2021
- Ceramide analogue 14S24 ((S)-2-tetracosanoylamino-3-hydroxypropionic acid tetradecyl ester) is effective in skin barrier repair in vitro. · 2004
Linked databases 14
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
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