Ingredient Dictionary

4-ETHYLPHENOL

4-ethylphenol is a member of the class of phenols carrying an ethyl substituent at position 4.

Definition

4-ethylphenol is a member of the class of phenols carrying an ethyl substituent at position 4. It has a role as a fungal xenobiotic metabolite.

Source: PubChem

US FDA substance register · UNII AGG7E6G0ZC · registered name 4-ETHYLPHENOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

4-ETHYLPHENOLINCIPhenol, 4-ethyl-Synonym

CAS No.chemical registry number: 123-07-9
EC No.EU chemical inventory number: 204-598-6
DTXSIDUS EPA chemical ID: DTXSID4021977
DTXCIDUS EPA compound ID: DTXCID801977

IUPAC: 4-Ethylphenol
Molecular formula: C8H10O
Molecular weight: 122.167 g/mol

Measured properties

Appearance: Liquid · Colorless or white solid, Yellows upon exposure to light, [HSDB]
Odour: POWERFUL WOODY-PHENOLIC, YET SOMEWHAT SWEET · MEDICINAL, PHENOLIC
Boiling point: 217.9 °C · 218.00 to 219.00 °C. @ 760.00 mm Hg
Melting point: 46 °C · 44.00 to 46.00 °C. @ 760.00 mm Hg
Solubility: SLIGHTLY SOL IN WATER, SOL IN ALC, ETHER, & BENZENE, SOL IN CARBON DISULFIDE, & ACETONE · In water, 4.90X10+3 mg/l at 25 °C
Density: 1.011 @ 20 °C
Dissociation constant: pK = 10.38 @ 20 °C · pK = 10.0 at 25 °C
Melting/freezing point: 37~48 ℃
Initial boiling point and range: 218~219 ℃
Flash point: 100 ℃
Upper/lower flammability or explosive limits: 6.7 / 1.1 %
Vapour pressure: 0.0372 ㎜Hg (at 25 C)
Vapour density: 4.2
Relative density: 0.984
n-Octanol/water partition coefficient (Kow): 2.58
Molecular weight: 122.17

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient3
Fragrance3
Cleaning agent2
Solvent2
Corrosion inhibitor1
Intermediate1
Processing aids not otherwise specified1
Surface modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 5 studies

Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
SkinSens1
Skin Sensitization · QSAR Predicted
Not classified
Skin Irritation · Screening
Category 1
Eye Irritation · Screening