4-HYDROXYPROPYLAMINO-3-NITROPHENOL

US FDA substance register · UNII X89W3M6X79 · registered name 4-HYDROXYPROPYLAMINO-3-NITROPHENOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Banned

South Korea

Restricted or banned

South Korea · Taiwan

Restricted

Taiwan · United Kingdom

Source: MFDS (Korea) cosmetic regulatory information · ASEAN Cosmetic Directive · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

ASEAN

• Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
• Maximum authorised concentration in the finished cosmetic product : (b) 2.6 %
• Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 2.6 % calculated as free base. For (a) and (b): • Do not use with nitrosating systems • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers The free base and salts of this hair colouring ingredient, unless prohibited under Annex II, are permitted for use. The direction for use “wear suitable gloves” must be included in label or leaflet text.

China

• Maximum concentration : 2.6%
• Maximum concentration : 2.6%

European Union

• Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
• Maximum concentration in ready for use preparation : (b) 2.6%
• Other : (a) After mixing under oxidative conditions the maximum use concentration applied to hair must not exceed 2.6% calculated as free base. For (a) and (b): - Do not use with nitrosating systems - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers
• Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary 'black henna’ tattoo in the past.

EU Cosmetics Regulation, Annex III (restricted substances), entry 205 · maximum concentration (b) 2.6% · applies to (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

EU Cosmetics Regulation, Annex III (restricted substances), entry 219 · maximum concentration (b) 2,6 % · applies to (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products

Source: EU restricted substances (Annex III)

Restriction III/205 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report on the Safety Assessment of Amino Nitrophenols Used in Hair Dyes

Source: US Cosmetic Ingredient Review (CIR)