Ingredient Dictionary

4-TERT-BUTYLCYCLOHEXANONE

Cyclohexanone, 4-(1,1-dimethylethyl)- is a cyclic ketone.

Definition

Cyclohexanone, 4-(1,1-dimethylethyl)- is a cyclic ketone.

Source: PubChem

US FDA substance register · UNII 4M45G11K23 · registered name 4-TERT-BUTYLCYCLOHEXANONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Gives the product a scentPERFUMING

Safety & regulatory references

Restricted: International fragrance standard (IFRA)

Source: IFRA fragrance standards

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

4-TERT-BUTYLCYCLOHEXANONEINCICyclohexanone, 4-(1,1-dimethylethyl)-Synonym

CAS No.chemical registry number: 98-53-3
EC No.EU chemical inventory number: 202-678-5
DTXSIDUS EPA chemical ID: DTXSID7044394
DTXCIDUS EPA compound ID: DTXCID5024394

IUPAC: 4-tert-Butylcyclohexan-1-one
Molecular formula: C10H18O
Molecular weight: 154.253 g/mol

Measured properties

Molecular weight: 154.28

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance3

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

SkinIrr2
Skin Irritation · QSAR Predicted
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to EPA OPPTS 870.2600 (Skin Sensitisation) adopted in 203 according to other guideline: CPMP/SWP/2145/00 adopted in 2001 according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) updated 2010 according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to