Ingredient Dictionary

4-TOSYLAMIDE

Toluene-4-sulfonamide is a sulfonamide that is benzenesulfonamide bearing a methyl group at position 4.

Definition

Toluene-4-sulfonamide is a sulfonamide that is benzenesulfonamide bearing a methyl group at position 4.

Source: PubChem

US FDA substance register · UNII I8266RI90M · registered name P-TOLUENESULFONAMIDE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

4-Tosylamide is the organic compound that conforms to the formula:

Cosmetic roles

Skin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUS

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

4-TOSYLAMIDEINCIBenzenesulfonamide, 4-methyl-Synonym

CAS No.chemical registry number: 70-55-3
DTXSIDUS EPA chemical ID: DTXSID8029105
DTXCIDUS EPA compound ID: DTXCID109105

IUPAC: 4-Methylbenzene-1-sulfonamide
Molecular formula: C7H9NO2S
Molecular weight: 171.21 g/mol

Measured properties

Appearance: solid
Colour: white
Melting/freezing point: 138 ℃
Initial boiling point and range: 221 ℃(at 10 mmHg)
Flash point: 202 ℃(c.c.)
Flammability (solid, gas): combustible
Vapour pressure: 0.1 ㎪ (at 70 ℃)
Water solubility: 0.316 ㎎/ℓ (@ 25 ℃)
Vapour density: 5.91
Relative density: 1.58 (@ 20 ℃)
n-Octanol/water partition coefficient (Kow): 0.84
Molecular weight: 171.2

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 12 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Plasticizer10
Processing aids not otherwise specified2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 0 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

SkinSens1
Skin Sensitization · QSAR Predicted
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)