Gloshell
成分辞典

成分辞典

5-AMINO-6-CHLORO-O-CRESOL

分子構造

定義

米国FDA 物質登録 · UNII 8077WHL3XK · 登録名 5-AMINO-6-CHLORO-O-CRESOL · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

化粧品での役割

髪を染めるHAIR DYEING微生物の増殖を抑えるANTIMICROBIAL

安全性・規制情報

制限
イギリス · 韓国

出典: ASEAN 化粧品指令 · EU 化粧品規則 · 韓国食薬処 化粧品規制情報 · 台湾FDA 化粧品成分 · 台湾FDA 化粧品規制 · 英国 化粧品規則

ASEAN

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted.
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.5 %
  • Other limitations and requirements : (a) After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.0 % (a) and (b): The direction for use “wear suitable gloves” must be included in label or leaflet text.
  • Conditions of use and warning which must be printed on the labels : (a) The mixing ratio must be printed on the label. Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary “black henna” tattoos may increase your risk of allergy. Do not colour your hair if: • you have a rash on your face or sensitive, irritated and damaged scalp, • you have ever experienced any reaction after colouring your hair, • you have experienced a reaction to a temporary “black henna” tattoo in the past (a) & (b) Do not use to dye eyelashes or eyebrows

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : (a)氧化性染髮產品 : 1%
  • (b)非氧化性染髮產品 : 0.5%

中国

  • 最大配合量 : 1%
  • 最大配合量 : 0.5%

欧州連合

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products
  • Maximum concentration in ready for use preparation : (b) 0.5 %
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past.”

出典: 韓国食薬処 化粧品規制情報

Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion on 2-Chloro-6-Methyl-3-Aminophenol Hydrochloride; Opinion on 5-Amino-6-chloro-o-cresol

出典: EU CosIng 成分リスト

Reviewed by CIR: Final Report: Amended Safety Assessment of 5-Amino-6-Chloro-o-Cresol as Used in Cosmetics

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol and 4-Chloro-2-Aminophenol

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

別名・識別情報

5-AMINO-6-CHLORO-O-CRESOLINCI5-아미노-6-클로로-o-크레솔韓国の表示名(食薬処標準名)
CAS No.化学物質登録番号
84540-50-1
EC No.EU化学物質目録番号
283-144-9
DTXSID米国EPA化学物質番号
DTXSID80233531
DTXCID米国EPA化合物番号
DTXCID10156022
IUPAC
3-Amino-2-chloro-6-methylphenol
分子式
C7H8ClNO
分子量
157.6 g/mol

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品5件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Dye3
  • Biocide2

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験2件・眼試験1件の記録があります。

低いと分類2件

試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験3件をすべて見る
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EPA OPPTS 870.2400 (Acute Eye Irritation) according to

出典: 米国EPA CompTox

関連文献

連携データベース 19