Ingredient Dictionary

6-AMINOCAPROIC ACID

6-aminohexanoic acid is an -amino acid comprising hexanoic acid carrying an amino substituent at position C-6.

Definition

6-aminohexanoic acid is an -amino acid comprising hexanoic acid carrying an amino substituent at position C-6. Used to control postoperative bleeding, and to treat overdose effects of the thrombolytic agents streptokinase and tissue plasminogen activator. It has a role as a metabolite, an antifibrinolytic drug and a hematologic agent. It is an epsilon-amino acid and an omega-amino fatty acid. It is functionally related to a hexanoic acid. It is a conjugate acid of a 6-aminohexanoate. It is a tautomer of a 6-aminohexanoic acid zwitterion.

Source: PubChem

US FDA substance register · UNII U6F3787206 · registered name Aminocaproic Acid · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

No declared roleNOT REPORTED

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 7

Source: EU prohibited substances (Annex II)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/7

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name アミノカプロン酸: 本品は、次の化学式で表されるアミノ酸である。

Source: JCIA labelling names (Japan)

Names & identifiers

6-AMINOCAPROIC ACIDINCI6-아미노카프로익애씨드Korean label name (MFDS standard)Hexanoic acid, 6-amino-Synonymアミノカプロン酸Japanese labelling name

CAS No.chemical registry number: 60-32-2
EC No.EU chemical inventory number: 200-469-3
DTXSIDUS EPA chemical ID: DTXSID0020070
DTXCIDUS EPA compound ID: DTXCID7070

IUPAC: 6-Aminohexanoic acid
Molecular formula: C6H13NO2
Molecular weight: 131.175 g/mol

Measured properties

Appearance: Wet Solid · White solid, [HSDB] White crystalline solid, [MSDSonline]
Odour: ODORLESS, OR NEARLY SO · odourless
Melting point: 205 °C · 202-203 °C
Solubility: 505000 mg/L (at 25 °C) · 1 G IN 3 ML OF WATER, SLIGHTLY SOL IN ALCOHOL, PRACTICALLY INSOL IN CHLOROFORM & ETHER
Stability: STABLE IN LIGHT & AIR
Dissociation constant: 4.43 (at 25 °C) · PK1= 4.43, PK2= 10.75
Colour: white
Melting/freezing point: 205 ℃
Flammability (solid, gas): flammable
Vapour pressure: 0.00000000301 ㎜Hg (@ 25 ℃, est.)
Water solubility: 505000 ㎎/ℓ (@ 25 ℃)
Vapour density: 4.53
Relative density: 0.8
n-Octanol/water partition coefficient (Kow): -2.95
Molecular weight: 131.18

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

No specific technical function1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 0 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 1 studies

SkinSens1
Skin Sensitization · QSAR Predicted