Acetaldehyde can cause cancer according to an independent committee of scientific and health experts.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 1 after it (usually 1% or less).
Products using this ingredient
1 of 1 confirmed · likeliest to carry enough first
Definition
Acetaldehyde can cause cancer according to an independent committee of scientific and health experts.
Source: PubChem
US FDA substance register · UNII GO1N1ZPR3B · registered name Acetaldehyde · single chemical substance
Acetaldehyde is the aldehyde that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H350 (category 1B) · H341 (category 2) · H319 (category 2) · +3 more
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1391
Restriction II/1391 · SCCS opinion: Opinion concerning Acetaldehyde
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 75-07-0
- EC No.EU chemical inventory number
- 200-836-8
- DTXSIDUS EPA chemical ID
- DTXSID5039224
- DTXCIDUS EPA compound ID
- DTXCID202
- IUPAC
- Acetaldehyde
- Molecular formula
- C2H4O
- Molecular weight
- 44.053 g/mol
Measured properties
- Appearance
- Acetaldehyde appears as a clear colorless liquid with a pungent choking odor. Flash point -36 °F. Boiling point 69 °F. Density 6.5 lb / gal. Vapors are heaver than air and irritate the mucous membranes and especially the eyes. Used to make other chemicals. · Liquid
- Odour
- Pungent, fruity odor · Pungent, suffocating odor that is somewhat fruity and quite pleasant in dilute concentrations.
- Boiling point
- 70 °F at 760 mmHg (NTP, 1992) · 20.8 °C
- Melting point
- -190.3 °F (NTP, 1992) · -123.4 °C
- Solubility
- 0.1 to 1.0 mg/mL at 66 °F (NTP, 1992) · Miscible with water /1X10+6 mg/L at 25 °C/
- Density
- 0.78 at 68 °F (USCG, 1999) - Less dense than water, will float · 0.7834 g/cu cm at 18 °C
- Colour
- colourless
- Melting/freezing point
- -123.5 ℃
- Initial boiling point and range
- 20.2 ℃
- Flash point
- -38 ℃
- Upper/lower flammability or explosive limits
- 60 / 4 %
- Vapour pressure
- 902 ㎜Hg(25℃)
- Water solubility
- 100 g/100㎖(25℃)
- Relative density
- 0.78
- n-Octanol/water partition coefficient (Kow)
- -0.34
- Auto-ignition temperature
- 185 ℃
- Viscosity
- 253000 P(g/㎝·s)(20 ℃)
- Molecular weight
- 44.05
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 46 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance20
- No specific technical function8
- Binder4
- Intermediate3
- Flavouring and nutrient2
- Solvent2
- Corrosion inhibitor2
- Processing aids not otherwise specified1
4 other uses
- Deodorizer1
- Monomers1
- Softener and conditioner1
- Degradant/impurity (EPA)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
7 skin studies and 5 eye studies are on record.
The studies disagree (the most common conclusion covers 40%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 12 studies
- Skin sensitization - Category 1B
Skin Sensitization · Screening - Category 1
Skin Sensitization · Screening - Not classified
Skin Irritation · Screening - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) and 96/54/EEC,B6 - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: 19 CFR, Chapter I, Sec 173.40 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Eye Irrit. 2
Eye Irritation · Screening - Category 2A
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Microbial metabolism of ethanol and acetaldehyde and clinical consequences · 1997
- Recent Findings in Acetaldehyde Emission from Leather · 2017
- Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice. · 2007
- Aldehyde dehydrogenase 2 activity affects symptoms produced by an intraperitoneal acetaldehyde injection, but not acetaldehyde lethality. · 2005
- Pathobiological effects of acetaldehyde in cultured human epithelial cells and fibroblasts. · 1994
Linked databases 26
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- EU SCCS safety opinions 2
- IARC carcinogen classification
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese