N-phenylacetamide is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a phenyl group.
How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 5 after it (usually 1% or less).
Products using this ingredient
5 of 5 confirmed · likeliest to carry enough first
Definition
US FDA substance register · UNII SP86R356CC · registered name Acetanilide · single chemical substance
N-phenylacetamide is a member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen is substituted by a phenyl group. It has a role as an analgesic. It is an anilide and a member of acetamides. It is functionally related to an acetic acid.
Source: PubChem
Acetanilid is the aromatic amide that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 103-84-4
- EC No.EU chemical inventory number
- 203-150-7
- DTXSIDUS EPA chemical ID
- DTXSID2022543
- DTXCIDUS EPA compound ID
- DTXCID602543
- IUPAC
- N-Phenylacetamide
- Molecular formula
- C8H9NO
- Molecular weight
- 135.166 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Odour
- odourless
- Melting/freezing point
- 114.3 ℃
- Initial boiling point and range
- 304 ℃
- Flash point
- 169 ℃(o.c.)
- Vapour pressure
- 0.00122 ㎜Hg (@ 25 ℃)
- Water solubility
- 6390 ㎎/ℓ (@ 25 ℃)
- Vapour density
- 4.65
- Relative density
- 1.2190 (@ 15 ℃)
- n-Octanol/water partition coefficient (Kow)
- 1.16
- Auto-ignition temperature
- (517~541 ℃)
- Molecular weight
- 135.17
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance2
- Deodorizer1
- Intermediate1
- Polymerization promoter1
- Stabilizing agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not classified
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - SkinSens1
Skin Sensitization · QSAR Predicted - Category 2B
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Failure of oral antipyretic drugs to alter normal human pain thresholds. · 1949
- Index · 1976
- CHRONIC ACETANILID POISONING FROM HARPER'S BRAIN FOOD. · 1907
- A CASE OF ACETANILID POISONING FROM HEADACHE CAPSULES, WITH EXTREME TACHYCARDIA THE DOMINANT SYMPTOM. · 1907
- A CASE OF ACETANILID POISONING FROM ABSORPTION. · 1906
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese