成分词典

ACETOPHENONE

Acetophenone is a methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group.

定义

Acetophenone is a methyl ketone that is acetone in which one of the methyl groups has been replaced by a phenyl group. It has a role as a xenobiotic, a photosensitizing agent and an animal metabolite.

来源: PubChem

美国FDA 物质登记 · UNII RK493WHV10 · 登记名称 Acetophenone · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Acetophenone is the organic compound that conforms to the formula:

化妆品中的作用

为产品增添香味PERFUMING登记为香料组成物质（并非表示其增香）FRAGRANCE

安全与法规参考

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

详细资料——标示名称、识别编号、物性、试验记录、文献

官方标示名称和定义

日本化妆品工业联合会标示名称アセトフェノン: 本品は、次の化学式で表される有機化合物である。

来源: 日本化妆品工业联合会标示名称

别名和识别信息

ACETOPHENONEINCIEthanone, 1-phenyl-同义名アセトフェノン日本标示名称

CAS No.化学物质登记号: 98-86-2
EC No.欧盟化学品目录编号: 202-708-7
DTXSID美国EPA化学品编号: DTXSID6021828
DTXCID美国EPA化合物编号: DTXCID501828

IUPAC: 1-Phenylethan-1-one
分子式: C8H8O
分子量: 120.151 g/mol

实测物性

性状: Acetophenone appears as a colorless liquid with a sweet pungent taste and odor resembling the odor of oranges. Freezes under cool conditions. Slightly soluble in water and denser than water. Hence sinks in water. Vapor heavier than air. A mild irritant to skin and eyes. Vapors can be narcotic in high concentrations. Used as a flavoring, solvent, and polymerization catalyst. · CBI, Liquid
气味: Sweet pungent odor · Sweet, pungent and strong medicinal odor
沸点: 395.1 °F at 760 mmHg (USCG, 1999) · 202.1 °C
熔点: 67.5 °F (USCG, 1999) · 19.4 °C
溶解性: In water, 6,130 mg/L at 25 °C · Slightly soluble in water
密度: 1.028 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.0281 g/cu cm at 20 °C
嗅觉阈值: 0.3 ppm
熔点/凝固点: 20 ℃
初沸点和沸程: 202 ℃
闪点: 77 ℃(c.c.)
蒸气压: 0.133 ㎪(15℃)
溶解度: 0.613 g/100㎖(25℃)
蒸气密度: 4.1
比重: 1.03
正辛醇/水分配系数（Kow）: 1.58
自燃温度: 571 ℃
黏度: 0.93 cP(20℃)
分子量: 120.1

这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。

来源: PubChem · 韩国安全保健公团安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 80 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。

Fragrance63
Flavouring and nutrient6
Intermediate3
Solvent2
Adsorbent2
Processing aids not otherwise specified1
Corrosion inhibitor1
No specific technical function1

其余用途 1 项

Deodorizer1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 5 项、眼部试验 5 项。

归类为中等1 项归类为低2 项

各项试验结论不一（最多的结论占 33%），因此不能断定该成分有刺激性。这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。

查看全部 10 项试验

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: Consumer Product Safety Commission of the USA, Code of Federal Regulations, Title 16, Section 1500.41 according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
Category 6.3A (Category 2)
Skin Irritation · Read Across
Classification not possible
Skin Sensitization · Screening
Category 2
Skin Irritation · Screening
Eye Irrit. 2
Eye Irritation · Authoritative
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to other guideline: Consumer Product Safety Commission of the USA, Code of Federal Regulations, Title 16, Section 1500.42 according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Category 2A
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across