Definition
US FDA substance register · UNII A1FJQ7D0K3 · registered name 2-ACETYLBENZOFURAN · single chemical substance
Cosmetic roles
Gives the product a scentPERFUMINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE
Safety & regulatory references
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
ACETYLBENZOFURANINCIEthanone, 1-(2-benzofuranyl)-Synonym
- CAS No.chemical registry number
- 1646-26-0
- EC No.EU chemical inventory number
- 216-706-9
- DTXSIDUS EPA chemical ID
- DTXSID3061845
- DTXCIDUS EPA compound ID
- DTXCID1035288
- IUPAC
- 1-(1-Benzofuran-2-yl)ethan-1-one
- Molecular formula
- C10H8O2
- Molecular weight
- 160.172 g/mol
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance2
- Deodorizer1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 1 eye studies are on record.
Classed as moderate2Classed as low2
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · equivalent or similar to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) pre-guideline - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1992 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) 29 Dec 1992 according to - Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.6 (Skin Sensitisation) Commission directive 92/69/EEC, 1992 - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) adopted in 1992 according to EU Method B.6 (Skin Sensitisation) Commission directive No 92/69/EEC, 1992 - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) (July, 2013) according to EU method B.47 (Bovine corneal opacity and permeability test method for identifying ocular corrosives and severe irritants) Commission Regulation (EU) No 1152/2010 according to
Source: US EPA CompTox dashboard
Linked databases 11
- AICIS inventory notices (Australia)
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- NIST Chemistry WebBook
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata