CI Acid Orange 3 is an organic molecular entity.
Definition
CI Acid Orange 3 is an organic molecular entity.
Source: PubChem
US FDA substance register · UNII P0XV7XM57J · registered name ACID ORANGE 3 · single chemical substance
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · China · European Union · South Korea · Taiwan · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction II/1280
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Acid Orange 3
Reviewed by CIR: Acid Orange 3
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酸性橙３: 本品は、次の化学式で表される頭髪用染料である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 6373-74-6
- EC No.EU chemical inventory number
- 228-921-5
- DTXSIDUS EPA chemical ID
- DTXSID1021081
- DTXCIDUS EPA compound ID
- DTXCID901081
- IUPAC
- Sodium 2-anilino-5-(2,4-dinitroanilino)benzene-1-sulfonate
- Molecular formula
- C18H13N4NaO7S
- Molecular weight
- 452.37 g/mol
Measured properties
- Appearance
- C.i. acid orange 3 is a brown to dark brown microcrystalline powder. (NTP, 1992) · Dark orange-brown solid, [HSDB]
- Melting point
- 399 to 403 °F (NTP, 1992)
- Solubility
- 1 to 10 mg/mL at 77 °F (NTP, 1992) · Very soluble in water and ethanol
- n-Octanol/water partition coefficient (Kow)
- 1.09
- Molecular weight
- 452.49
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye3
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
Linked databases 23
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata