Ingredient Dictionary

ACID YELLOW 36

Metanil yellow is an organic sodium salt having 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate as the counterion.

Definition

Metanil yellow is an organic sodium salt having 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate as the counterion. Used in one variant of Masson's trichrome to stain collagen yellow in contrast to the red muscle, but is not in common used. It has a role as a histological dye. It contains a 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate.

Source: PubChem

US FDA substance register · UNII 7SPF5O5BW8 · registered name METANIL YELLOW · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Dyes hairHAIR DYEING

Safety & regulatory references

Banned: ASEAN · Canada · China · European Union · South Korea · United Kingdom
Restricted or banned: Argentina · ASEAN · Brazil · Canada · China · European Union · Japan · South Korea
Allowed colourant: United States

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS) · US FDA prohibited and restricted ingredients

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 387

Source: EU prohibited substances (Annex II)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/387

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

ACID YELLOW 36INCI산성황색36호Korean label name (MFDS standard)Benzenesulfonic acid, 3-[[4-(phenylamino)phenyl]azo]-, monosodium saltSynonym

CAS No.chemical registry number: 587-98-4
EC No.EU chemical inventory number: 209-608-2
DTXSIDUS EPA chemical ID: DTXSID5041722
DTXCIDUS EPA compound ID: DTXCID901506490

IUPAC: Sodium 3-[(4-anilinophenyl)diazenyl]benzene-1-sulfonate
Molecular formula: C18H14N3NaO3S
Molecular weight: 375.38 g/mol

Measured properties

Appearance: solid
Molecular weight: 375.38

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 34 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye29
Pigment5

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 2 eye studies are on record.

Classed as highly irritating1Classed as low1

The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Federal Register 38 No 187 s 1500 .41 (skin) according to
High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Federal Register 38 s 15 .00 42 (Eye), p. 27019 of 27 .09 .73. according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across