Adenosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having adenine as the nucleobase.
How much products actually contain
No product states its amount yet.
Of the products containing it, 1 list it before the 1% line and 3 after it (usually 1% or less).
Products using this ingredient
4 of 4 confirmed · likeliest to carry enough first
Definition
Adenosine 5'-monophosphate is a purine ribonucleoside 5'-monophosphate having adenine as the nucleobase. It has a role as a cofactor, a micronutrient, a nutraceutical, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an EC 3.1.3.11 (fructose-bisphosphatase) inhibitor, an adenosine A1 receptor agonist and a fundamental metabolite. It is a purine ribonucleoside 5'-monophosphate and an adenosine 5'-phosphate. It is a conjugate base of an adenosine 5'-monophosphate(1+). It is a conjugate acid of an adenosine 5'-monophosphate(2-).
Source: PubChem
US FDA substance register · UNII 415SHH325A · registered name ADENOSINE PHOSPHATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Safety Assessment of Adenosine as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アデノシンリン酸: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 61-19-8
- EC No.EU chemical inventory number
- 200-500-0
- DTXSIDUS EPA chemical ID
- DTXSID5022560
- DTXCIDUS EPA compound ID
- DTXCID002560
- IUPAC
- 5'-Adenylic acid
- Molecular formula
- C10H14N5O7P
- Molecular weight
- 347.224 g/mol
Measured properties
- Appearance
- Solid · CRYSTALS FROM WATER + ACETONE
- Melting point
- 195 dec °C · 196-200 °C
- Solubility
- 10000 mg/L (at 20 °C) · ALMOST INSOL IN COLD H2O /YEAST ADENYLIC ACID MONO-HCL/
- Stability
- FREE ACID & ITS SALTS ARE STABLE FOR LONG PERIODS IN DRY STATE, NEUTRAL SOLN ARE ALSO STABLE
- Dissociation constant
- PK1= 3.8, PK2= 6.2
- Colour
- colourless
- Melting/freezing point
- 72.5 ℃
- Initial boiling point and range
- 180 ℃(at 0.22 mm Hg)
- Flash point
- 210 ℃(closed cup)
- Vapour pressure
- 0.000000061 ㎜Hg
- Water solubility
- (7.5E-005mg/L(25℃), est.)
- Vapour density
- 11.3
- Relative density
- 0.8063 (at 75 ℃)
- n-Octanol/water partition coefficient (Kow)
- 9.68
- Molecular weight
- 326.6
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner3
Source: US EPA CompTox dashboard
Related literature
- The effects of the ointment of compound cyclic adenosine phosphate on the mice models of psoriasis · 2007
- Safety Assessment of Adenosine as Used in Cosmetics · 2023
- Nano-TiO₂ Reduces Testosterone Production in Primary Cultured Leydig Cells from Rat Testis Through the Cyclic Adenosine Phosphate/Cyclic Guanosine Phosphate/Epidermal Growth Factor Receptor/Matrix Metalloproteinase Signaling Pathway. · 2021
- Humoral Responses of Smooth Muscle from Rabbit Subarachnoid Artery Compared to Kidney, Mesentery, Lung, Heart, and Skin Vascular Smooth Muscle · 1972
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese