Ingredient Dictionary

ADIPIC ACID

Adipic acid is an alpha,-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane.

How much products actually contain

No product states its amount yet.

Of the products containing it, 4 list it before the 1% line and 4 after it (usually 1% or less).

Products using this ingredient

8 of 8 confirmed · likeliest to carry enough first

Definition

Adipic acid is an alpha,-dicarboxylic acid that is the 1,4-dicarboxy derivative of butane. It has a role as a food acidity regulator and a human xenobiotic metabolite. It is a dicarboxylic fatty acid and an alpha,omega-dicarboxylic acid. It is a conjugate acid of an adipate(1-).

Source: PubChem

US FDA substance register · UNII 76A0JE0FKJ · registered name Adipic Acid · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Listed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCEKeeps pH steadyBUFFERING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Final Report of the Cosmetic Ingredient Review Expert Panel on the Safety Assessment of Dicarboxylic Acids, Salts and Esters

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name アジピン酸: 本品は、次の化学式で表されるジカルボン酸である。

Source: JCIA labelling names (Japan)

Names & identifiers

ADIPIC ACIDINCI아디픽애씨드Korean label name (MFDS standard)Hexanedioic acidSynonymアジピン酸Japanese labelling name

CAS No.chemical registry number: 124-04-9
EC No.EU chemical inventory number: 204-673-3
DTXSIDUS EPA chemical ID: DTXSID7021605
DTXCIDUS EPA compound ID: DTXCID301605

IUPAC: Hexanedioic acid
Molecular formula: C6H10O4
Molecular weight: 146.142 g/mol

Measured properties

pH: 2.7
Melting/freezing point: 152 ℃
Initial boiling point and range: 338 ℃
Flash point: 196 ℃(c.c.)
Upper/lower flammability or explosive limits: 9.6 / 1.6 %
Vapour pressure: 10 ㎜Hg (18.5℃)
Water solubility: 1.4 g/100㎖
Vapour density: 5.04
Relative density: 1.366
n-Octanol/water partition coefficient (Kow): 0.08
Auto-ignition temperature: 422 ℃

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 60 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Plasticizer8
Monomers7
Softener and conditioner6
Flavouring and nutrient6
Processing aids not otherwise specified5
pH regulating agent4
Solvent3
Intermediate3

14 other uses

Thickening agent2
Flocculating agent2
Lubricating agent2
Deodorizer2
Hardener1
Catalyst1
Solids separation (precipitating) agent, not other1
Elasticizer1
Sizing agent1
Flotation agent1
Other1
Stabilizing agent1
Leavening agent (EPA)1
Fragrance1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 5 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 7 studies

Not classified
Skin Irritation · Screening
Classification not possible
Skin Sensitization · Screening
Eye Irrit. 2
Eye Irritation · Authoritative
Serious eye damage/eye irritation - Category 2A
Eye Irritation · Screening
Category 2A
Eye Irritation · Screening
Eye damage - category 1
Eye Irritation · Screening
Category 6.4A (Category 2A)
Eye Irritation · Read Across