What is this ingredient?

미국 FDA 물질 등록 · UNII 9XP4LC555B · 등록명 ISOMETHYL-.ALPHA.-IONONE · 단일 화학물질

All ingredients

Ingredient Dictionary

ALPHA-ISOMETHYL IONONE

3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one is a sesquiterpenoid.

How much products actually contain

No product states its amount yet.

Of the products containing it, 31 list it before the 1% line and 595 after it (usually 1% or less).

Products using this ingredient

12 of 626 confirmed · likeliest to carry enough first · See all 626

Definition

US FDA substance register · UNII 9XP4LC555B · registered name ISOMETHYL-.ALPHA.-IONONE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

3-Methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one is a sesquiterpenoid.

Source: PubChem

Alpha-Isomethyl Ionone is the organic compound that conforms to the formula

Cosmetic roles

Gives the product a scentPERFUMINGKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONING

Safety & regulatory references

Restricted: United Kingdom

Source: EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

European Union

Other : The presence of the substance must be indicated in the list of ingredients referred to in Article 19(1)g when its concentration exceeds: - 0.001% in leave-on products - 0.01% in rinse-off products

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 90

Source: EU restricted substances (Annex III)

Restriction III/90 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name α－イソメチルイオノン: 本品は、次の化学式で表される環式ケトン化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

ALPHA-ISOMETHYL IONONEINCI알파-아이소메틸아이오논Korean label name (MFDS standard)3-Buten-2-one, 3-methyl-4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-Synonymα－イソメチルイオノンJapanese labelling name

CAS No.chemical registry number: 127-51-5
EC No.EU chemical inventory number: 204-846-3
DTXSIDUS EPA chemical ID: DTXSID7027047
DTXCIDUS EPA compound ID: DTXCID00809691

IUPAC: 3-Methyl-4-(2,6,6-trimethylcyclohex-2-en-1-yl)but-3-en-2-one
Molecular formula: C14H22O
Molecular weight: 206.329 g/mol

Measured properties

Appearance: solid
Colour: white
Odour: odourless
Melting/freezing point: 202~203 ℃
Vapour density: 7.12
n-Octanol/water partition coefficient (Kow): 4.7
Molecular weight: 206.327

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 796 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Fragrance788
Flavouring and nutrient4
Deodorizer3
Softener and conditioner1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 4 eye studies are on record.

Classed as highly irritating4Classed as low1

The study conclusions largely agree (80%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 8 studies

High Frequency of Sensitization
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as mentioned below
Severe Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Severe Irritation
skin irritation: in vivo · Screening · other guideline: Annex V of EEC directive 79/831 according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: see Principles below according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to