成分词典

AMBROXIDE

Ambroxan is a diterpenoid derived from sclareol that is responsible for the odour of ambergris (a solid, waxy, flammable substance produced in the digestive system of sperm whales).

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中，0 款将其列在 1% 线之前，2 款列在之后（通常不超过 1%）。

含有此成分的产品

已确认 2 款中的 2 款 · 按含量充足程度排序

定义

Ambroxan is a diterpenoid derived from sclareol that is responsible for the odour of ambergris (a solid, waxy, flammable substance produced in the digestive system of sperm whales). It is a diterpenoid and an organic heterotricyclic compound.

来源: PubChem

美国FDA 物质登记 · UNII TD34B3O8M9 · 登记名称 AMBROXIDE, (-)- · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Ambroxide is the heterocyclic compound that conforms to the formula:

化妆品中的作用

为产品增添香味PERFUMING登记为香料组成物质（并非表示其增香）FRAGRANCE

安全与法规参考

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

AMBROXIDEINCINaphtho[2,1-b]furan, dodecahydro-3a,6,6,9a-tetramethyl-, [3aR-(3a.alpha.,5a.beta.,9a.alpha.,9b.beta.)]-同义名

CAS No.化学物质登记号: 6790-58-5
DTXSID美国EPA化学品编号: DTXSID0047113
DTXCID美国EPA化合物编号: DTXCID8027113

IUPAC: (3aR,5aS,9aS,9bR)-3a,6,6,9a-Tetramethyldodecahydronaphtho[2,1-b]furan
分子式: C16H28O
分子量: 236.399 g/mol

实测物性

性状: CBI, Liquid
颜色: 白色
熔点/凝固点: 73~77 ℃
初沸点和沸程: 273.9 ℃
闪点: 104.8 ℃
蒸气压: 0.00393 ㎜Hg (估算值)
溶解度: 2.436 ㎎/ℓ
比重: 0.939
分子量: 236.39

这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。

来源: PubChem · 韩国安全保健公团安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 35 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。

Fragrance31
Flavouring and nutrient2
Deodorizer2

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 5 项、眼部试验 2 项。

归类为低6 项

试验结论基本一致（100%）。这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。

查看全部 7 项试验

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (Adopted 12th May 1981) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (Adopted in March 1984) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (Adopted 12th May 1981) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) (Adpoted in 12th May 1981) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) (Adopted in March 1984) according to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) (Adopted in May 1981) according to EU Method B.6 (Skin Sensitisation) (Adopted in March 1984)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) (Adopted February 24, 1987) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: 16 C.F.R. s 1500.42 Test for eye irritants. according to