Amentoflavone is a biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring.
定義
Amentoflavone is a biflavonoid that is obtained by oxidative coupling of two molecules of apigenin resulting in a bond between positions C-3 of the hydroxyphenyl ring and C-8 of the chromene ring. A natural product found particularly in Ginkgo biloba and Hypericum perforatum. It has a role as an antiviral agent, an angiogenesis inhibitor, a P450 inhibitor, a cathepsin B inhibitor and a plant metabolite. It is a hydroxyflavone, a ring assembly and a biflavonoid.
出典: PubChem
米国FDA 物質登録 · UNII 9I1VC79L77 · 登録名 AMENTOFLAVONE · 単一の化学物質
Amentoflavone
化粧品での役割
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
別名・識別情報
- CAS No.化学物質登録番号
- 1617-53-4
- DTXSID米国EPA化学物質番号
- DTXSID20167225
- DTXCID米国EPA化合物番号
- DTXCID1089716
- IUPAC
- 8-[5-(5,7-Dihydroxy-4-oxo-4H-1-benzopyran-2-yl)-2-hydroxyphenyl]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- 分子式
- C30H18O10
- 分子量
- 538.464 g/mol
製品が実際に使っている用途
米国EPAにこの成分を届け出た製品2件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。
- Bleaching agent1
- Antioxidant1
出典: 米国EPA CompTox
関連文献
- Selaginella tamariscina extract and amentoflavone ameliorate UVB-induced skin aging via AMPK activation. · 2026
- Amentoflavone mitigates UVB-induced epidermal photoaging by antagonizing PAR2-driven PI3K/Akt/FoxO6 oxidative-stress signaling. · 2026
- Analysis of Nonclinical Safety and Corneal Pain-Inducing Potential of Amentoflavone (AMT) in Adult Zebrafish (Danio rerio). · 2025
- Amentoflavone-Enriched Selaginella rossii Protects against Ultraviolet- and Oxidative Stress-Induced Aging in Skin Cells · 2022
- Amentoflavone as an Ally in the Treatment of Cutaneous Leishmaniasis: Analysis of Its Antioxidant/Prooxidant Mechanisms · 2021