What is this ingredient?

미국 FDA 물질 등록 · UNII CZ7BU4QZJZ · 등록명 AMINOMETHYL PROPANEDIOL · 단일 화학물질

Ingredient Dictionary

AMINOMETHYL PROPANEDIOL

2-amino-2-methylpropane-1,3-diol is an aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.

How much products actually contain

No product states its amount yet.

Of the products containing it, 38 list it before the 1% line and 21 after it (usually 1% or less).

Products using this ingredient

12 of 58 confirmed · likeliest to carry enough first · See all 58

Definition

US FDA substance register · UNII CZ7BU4QZJZ · registered name AMINOMETHYL PROPANEDIOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

2-amino-2-methylpropane-1,3-diol is an aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.

Source: PubChem

Aminomethyl Propanediol is a substituted aliphatic diol that conforms to the formula.

Cosmetic roles

Keeps pH steadyBUFFERINGListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction III/61

Source: EU CosIng ingredient list

Reviewed by CIR: Safety Assessment of Tromethamine, Aminomethyl Propanediol and Aminoethyl Propanediol as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name ＡＭＰＤ: 本品は、次の化学式で表される脂肪族二価アルコールの誘導体である。

Source: JCIA labelling names (Japan)

Names & identifiers

AMINOMETHYL PROPANEDIOLINCI아미노메틸프로판다이올Korean label name (MFDS standard)1,3-Propanediol, 2-amino-2-methyl-SynonymＡＭＰＤJapanese labelling name

CAS No.chemical registry number: 115-69-5
EC No.EU chemical inventory number: 204-100-7
DTXSIDUS EPA chemical ID: DTXSID7059430
DTXCIDUS EPA compound ID: DTXCID8033356

IUPAC: 2-Amino-2-methylpropane-1,3-diol
Molecular formula: C4H11NO2
Molecular weight: 105.137 g/mol

Measured properties

Appearance: solid
Colour: white
Melting/freezing point: 109.5~110.5 ℃
Initial boiling point and range: 259.1~260.1 ℃ (102.2 kPa)
Vapour pressure: 0.023 ㎩ (25 °C)
Water solubility: 1000000 ㎎/ℓ (25 °C)
Relative density: 1200 kg/m³
n-Octanol/water partition coefficient (Kow): -3.3 (22.3 °C, pH:7)
Auto-ignition temperature: &amp, gt, 400 ℃ ( 1 atm)
Molecular weight: 105.136

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 12 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

pH regulating agent4
Fragrance2
Lubricating agent2
Intermediate1
Pigment1
Processing aids not otherwise specified1
Solvent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 2 eye studies are on record.

Classed as highly irritating1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Skin corrosion/irritation - Category 1
Skin Irritation · Screening
Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 6.4A (Category 2A)
Eye Irritation · Read Across
Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening