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Ingredients

Ingredient Dictionary

AMINOMETHYL PROPANOL

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 161 list it before the 1% line and 204 after it (usually 1% or less).

Products using this ingredient

12 of 362 confirmed · likeliest to carry enough first · See all 362

Definition

US FDA substance register · UNII LU49E6626Q · registered name AMINOMETHYLPROPANOL · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Keeps pH steadyBUFFERING

Safety & regulatory references

Restricted or banned
China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

  • Maximum concentration permitted at final product : Under maximum secondary amine: 0.5%
  • Other limitations and requirements : No use with nitrosating systems. Minimum 99% -Pureza. Maximum -Tenor of secondary amines in raw materials 0.5%. Maximum nitrosamine -Tenor: 50 ug / kg. -Envasar / Nitrite - free store in containers.

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : Maximum secondary amine content: 0.5%
  • Other limitations and requirements : • Do not use with nitrosating systems • Minimum purity: 99% • Maximum secondary amine content: 0.5% (applies to raw materials) • Maximum nitrosamine content: 50 μg/kg • Keep in nitrite-free containers

European Union

  • Maximum concentration in ready for use preparation : Maximum secondary amine content: 0.5%
  • Other : - Do not use with nitrosating systems - Minimum purity: 99% - Maximum secondary amine content: 0.5% (applies to raw materials) - Maximum nitrosamine content: 50 microgram/kg - Keep in nitrite-free containers

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction III/61

Source: EU CosIng ingredient list

Reviewed by CIR: Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name AMP: 本品は、次の化学式で表される脂肪族アルコールの誘導体である。

Source: JCIA labelling names (Japan)

Names & identifiers

AMINOMETHYL PROPANOLINCI아미노메틸프로판올Korean label name (MFDS standard)1-Propanol, 2-amino-2-methyl-SynonymAMPJapanese labelling name
CAS No.chemical registry number
124-68-5
EC No.EU chemical inventory number
204-709-8
DTXSIDUS EPA chemical ID
DTXSID8027032
DTXCIDUS EPA compound ID
DTXCID407032
IUPAC
2-Amino-2-methylpropan-1-ol
Molecular formula
C4H11NO
Molecular weight
89.138 g/mol

Measured properties

pH
11.3
Melting/freezing point
25~26 ℃
Initial boiling point and range
166 ℃
Flash point
67 ℃(c.c.)
Vapour pressure
1 ㎜Hg (20℃)
Water solubility
100 g/100㎖ (25℃)
Vapour density
3
Relative density
0.934
n-Octanol/water partition coefficient (Kow)
-0.74 (est.)
Molecular weight
89.14

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 149 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • pH regulating agent56
  • Dispersing agent28
  • Processing aids not otherwise specified16
  • Solvent12
  • Corrosion inhibitor8
  • Preservative6
  • Degradant/impurity (EPA)4
  • Catalyst2
12 other uses
  • Biocide2
  • Flotation agent2
  • Lubricating agent2
  • Deodorizer2
  • Pigment2
  • Binder1
  • Emulsifier1
  • Monomers1
  • Surfactant (surface active agent)1
  • Surface modifier1
  • Intermediate1
  • Filler1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 3 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 10 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
  • Skin corrosion/irritation - Category 1
    Skin Irritation · Screening
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Category 2
    Skin Irritation · Screening
  • Not classified
    Skin Sensitization · Screening
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • Category 1
    Eye Irritation · Screening
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Eye Irrit. 2
    Eye Irritation · Authoritative

Source: US EPA CompTox dashboard

Related literature

Linked databases 20