Definition
US FDA substance register · UNII 7MRY0C9SB6 · registered name 3-(TRIMETHOXYSILYL)PROPYLAMINE · single chemical substance
Aminopropyl Trimethoxysilane is the silicon compound that conforms to the formula
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アミノプロピルトリメトキシシラン: 本品は、次の化学式で表されるケイ素化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 13822-56-5
- EC No.EU chemical inventory number
- 237-511-5
- DTXSIDUS EPA chemical ID
- DTXSID0038833
- DTXCIDUS EPA compound ID
- DTXCID8018833
- IUPAC
- 3-(Trimethoxysilyl)propan-1-amine
- Molecular formula
- C6H17NO3Si
- Molecular weight
- 179.291 g/mol
Measured properties
- Appearance
- Liquid · Clear to straw-colored liquid with an ammoniacal odor, [Gelest MSDS]
- Colour
- colourless
- Initial boiling point and range
- 91~92 ℃ (at 15 mmHg)
- Flash point
- 83 ℃
- Relative density
- 1.01 ()
- Molecular weight
- 179.29
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 50 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Adhesion/cohesion promoter30
- Chemical reaction regulator6
- Hardener4
- Dispersing agent2
- Processing aids not otherwise specified2
- Sealant (barrier)2
- Monomers1
- Wetting agent (non-aqueous)1
2 other uses
- Intermediate1
- Plating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Category 6.3A (Category 2)
Skin Irritation · Read Across - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata