Ammonium acetate is an ammonium salt obtained by reaction of ammonia with acetic acid.
Definition
Ammonium acetate is an ammonium salt obtained by reaction of ammonia with acetic acid. A deliquescent white crystalline solid, it has a relatively low melting point (114C) for a salt. Used as a food acidity regulator, although no longer approved for this purpose in the EU. It has a role as a buffer and a food acidity regulator. It is an ammonium salt and an acetate salt.
Source: PubChem
US FDA substance register · UNII RRE756S6Q2 · registered name AMMONIUM ACETATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酢酸アンモニウム: 本品は、酢酸のアンモニウム塩であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 631-61-8
- EC No.EU chemical inventory number
- 211-162-9
- DTXSIDUS EPA chemical ID
- DTXSID5023873
- DTXCIDUS EPA compound ID
- DTXCID203873
- IUPAC
- Ammonium acetate
- Molecular formula
- C2H7NO2
- Molecular weight
- 77.083 g/mol
Measured properties
- Appearance
- Ammonium acetate appears as a white crystalline solid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. It is used in chemical analysis, in pharmaceuticals, in preserving foods, and for other uses. · CBI, Dry Powder, Liquid, Other Solid
- Odour
- SLIGHT ACETOUS ODOR
- Melting point
- 237.2 °F (USCG, 1999) · 114 °C
- Solubility
- SOL IN LESS THAN 1 PART WATER, FREELY SOL IN ALCOHOL, SLIGHTLY SOL IN ACETONE. · 148 G/100 CC WATER AT 4 °C, 7.89 G/100 CC METHANOL AT 15 °C
- Density
- 1.17 at 68 °F (USCG, 1999) - Denser than water, will sink · SP GR: 1.17 AT 20 °C/4 °C
- Stability
- DELIQUESCENT, TENDS TO LOSE AMMONIA.
- pH
- VERY CONCENTRATED SOLN IS SLIGHTLY ACID & 0.5 MOLAR AQ SOLN HAS PH 7.0. · 7.0
- Colour
- white
- Melting/freezing point
- 114 ℃
- Vapour pressure
- 0.000131 ㎜Hg (25℃(est.))
- Water solubility
- 100 g/100㎖ (25℃(est.))
- Relative density
- 1.073-1.17
- n-Octanol/water partition coefficient (Kow)
- -2.79 (est.)
- Molecular weight
- 77.08
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 15 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent6
- Catalyst2
- Soil amendments2
- Thickening agent1
- Anti-freeze agent1
- Photosensitive agent1
- Intermediate1
- Solids separation (precipitating) agent, not other1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Category 6.3B (Category 3)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
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- Development and validation of an LC-MS/MS method for the determination of adapalene in pharmaceutical forms for skin application · 2016
- High Performance Liquid Chromatography Tandem Mass Spectrometry Measurement of Bimatoprost, Latanoprost and Travoprost in Eyelash Enhancing Cosmetic Serums · 2016
- Determination of Acid Orange 7 and Auramine O in Some Cosmetics by High Performance Liquid Chromatography · 2012
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese