成分词典

AMYL ETHYL KETONE

3-octanone is a dialkyl ketone that is octane in which the two methylene protons at position 3 have been replaced by an oxo group.

定义

3-octanone is a dialkyl ketone that is octane in which the two methylene protons at position 3 have been replaced by an oxo group. It has a role as an antifeedant, an insect attractant, a toxin, a biomarker, a plant metabolite, a fungal metabolite and a human urinary metabolite. It derives from a hydride of an octane.

来源: PubChem

美国FDA 物质登记 · UNII 79173B4107 · 登记名称 3-OCTANONE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

化妆品中的作用

为产品增添香味PERFUMING

安全与法规参考

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

详细资料——标示名称、识别编号、物性、试验记录、文献

别名和识别信息

AMYL ETHYL KETONEINCI3-Octanone同义名

CAS No.化学物质登记号: 106-68-3
EC No.欧盟化学品目录编号: 203-423-0
DTXSID美国EPA化学品编号: DTXSID3041954
DTXCID美国EPA化合物编号: DTXCID1021954

IUPAC: Octan-3-one
分子式: C8H16O
分子量: 128.215 g/mol

实测物性

性状: Ethyl n-amyl ketone appears as a clear colorless liquid with a pungent odor. Insoluble in water and partially soluble in alcohol. Vapors are denser than air and may have a narcotic effect in high concentrations. Used in making perfumes and as a solvent for nitrocellulose and vinyl resins. · Liquid
气味: Mild fruity odor
沸点: 332.6 to 334.4 °F at 760 mmHg (USCG, 1999) · 167.5 °C
熔点: -23.00 °C. @ 760.00 mm Hg
溶解性: Slightly miscible (USCG, 1999) · Miscible with ethanol, ether
密度: 0.822 (USCG, 1999) - Less dense than water, will float · 0.820-0.824 at 20 °C/20 °C
颜色: 无色
熔点/凝固点: -18.5 ℃
初沸点和沸程: 167 ℃(at 749㎜Hg)
闪点: 43 ℃
蒸气压: 2 ㎜Hg (at 20℃)
溶解度: 2600 ㎎/ℓ
蒸气密度: 4.4
比重: 0.8221
正辛醇/水分配系数（Kow）: 2.22 ((估算值))
自燃温度: 330 ℃
黏度: (0.9 mPas (20 C))
分子量: 128.21

这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。

来源: PubChem · 韩国安全保健公团安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 9 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。

Fragrance7
Flavouring and nutrient2

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 5 项、眼部试验 2 项。

归类为刺激性高1 项归类为中等1 项归类为低2 项

各项试验结论不一（最多的结论占 25%），因此不能断定该成分有刺激性。这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。

查看全部 7 项试验

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) adopted 22 July 2010 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) No. 440/2008
Not classified
Skin Sensitization · Screening
Category 2
Skin Irritation · Screening
Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted 24 April 2002) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) No. 440/2008 according to
Category 6.3B (Category 3)
Skin Irritation · Read Across
Classification not possible
Eye Irritation · Screening
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 24 April 2002 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) No. 440/2008 according to