Anisole is a monomethoxybenzene that is benzene substituted by a methoxy group.
定义
Anisole is a monomethoxybenzene that is benzene substituted by a methoxy group. It has a role as a plant metabolite.
来源: PubChem
美国FDA 物质登记 · UNII B3W693GAZH · 登记名称 Anisole · 单一化学物质
化妆品中的作用
为产品增添香味PERFUMING
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
ANISOLEINCIBenzene, methoxy-同义名
- CAS No.化学物质登记号
- 100-66-3
- EC No.欧盟化学品目录编号
- 202-876-1
- DTXSID美国EPA化学品编号
- DTXSID4041608
- DTXCID美国EPA化合物编号
- DTXCID2021608
- IUPAC
- Anisole
- 分子式
- C7H8O
- 分子量
- 108.14 g/mol
实测物性
- 性状
- Anisole appears as a clear straw-colored liquid with an aromatic odor. Insoluble in water and the same density as water. Vapors heavier than air. Moderately toxic by ingestion. A skin irritant. Used to make perfumes, flavorings and as a solvent. · Liquid
- 气味
- SWEET ANISE-LIKE ODOR · Agreeable aromatic odor
- 沸点
- 155.5 °C AT 760 MM HG · 153.00 to 155.00 °C. @ 760.00 mm Hg
- 熔点
- -37.3 °C · -37.5 °C
- 溶解性
- SOLUBLE IN ALCOHOL AND ETHER · VERY SOLUBLE IN ACETONE
- 密度
- 0.9956 AT 18 °C/4 °C · PER CENT IN SATURATED AIR: 0.41, DENSITY OF SATURATED AIR: 1.1 (AIR= 1)
- 黏度
- 1.52 centipoise at 15 °C, 0.778 centipoise at 30 °C
- 熔点/凝固点
- -38.5 ℃
- 初沸点和沸程
- 155 ℃
- 闪点
- 52 ℃(o.c.)
- 蒸气压
- 0.47 ㎪ (at 25 C)
- 蒸气密度
- 3.7 ()
- 比重
- 0.9961 ()
- 正辛醇/水分配系数(Kow)
- 2.11
- 自燃温度
- 475 ℃
- 分子量
- 108.14
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 5 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Fragrance2
- Flavouring and nutrient2
- Solvent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 5 项、眼部试验 3 项。
归类为中等1 项归类为低1 项
各项试验结论不一(最多的结论占 50%),因此不能断定该成分有刺激性。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 8 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Moderate or Mild Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Category 6.3B (Category 3)
Skin Irritation · Read Across - Classification not possible
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to - Classification not possible
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across
来源: 美国EPA CompTox
相关文献
- Storage stable tretinoin and 4-hydroxy anisole containing topical composition · 2001
- Exploring the Therapeutic Effects of Anisole on Psoriasis in Mice Based on the JAK1/STAT3 Pathway · 2025
- A fast and reliable method to quantify neral and geranial (citral) in essential oils using 1H NMR spectroscopy · 2023
- Novel Application of Natural Anisole Compounds as Enhancers for Transdermal Delivery of Ligustrazine. · 2015
- Scientific Opinion on the safety and efficacy of aromatic ethers including anisole derivatives (chemical group 26) when used as feed additives for all animal species. · 2012