Apigenin is a trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7.
How much products actually contain
No product states its amount yet.
Of the products containing it, 11 list it before the 1% line and 6 after it (usually 1% or less).
Products using this ingredient
12 of 15 confirmed · likeliest to carry enough first · See all 15
Camille RoseCamille Rose Rejuva Drops - Come Back!
Not Your Mother'sNot Your Mother's Leave-In Conditioner
MoroccanoilMoroccanoil Oily Scalp Treatment
JVN HairJVN Hair Perfèct The Essential Dry Shampoo
JVN HairJVN Hair Perfèct The Essential Dry Shampoo Travel
The OrdinaryHair Care Multi-Peptide Serum for Hair Density 60ml
R+CoR+Co DALLAS Thickening Spray
R+CoR+Co DALLAS Thickening Spray - Mini
VerbVerb Sculpting Clay
OUAIOUAI Scalp & Body Scrub Melrose Place
OUAIOUAI Scalp and Body Scrub Melrose Place - Travel
R+CoR+Co DALLAS Biotin Thickening Treatment
Definition
Apigenin is a trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. It induces autophagy in leukaemia cells. It has a role as a metabolite and an antineoplastic agent. It is a conjugate acid of an apigenin-7-olate.
Source: PubChem
US FDA substance register · UNII 7V515PI7F6 · registered name APIGENIN · single chemical substance
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アピゲニン: 本品は、次の化学式で表される複素環式化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 520-36-5
- EC No.EU chemical inventory number
- 208-292-3
- DTXSIDUS EPA chemical ID
- DTXSID6022391
- DTXCIDUS EPA compound ID
- DTXCID902391
- IUPAC
- 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
- Molecular formula
- C15H10O5
- Molecular weight
- 270.24 g/mol
Measured properties
- Appearance
- Solid · Yellow needles from aqueous pyridine
- Melting point
- 345-350 °C · MP: 347.5 °C
- Solubility
- Soluble in ethanol, pyridine, concentrated sulfuric acid, very soluble in dilute alkalies · Moderately soluble in hot alcohol. Soluble in dilute KOH with intense yellow color
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Antioxidant1
Source: US EPA CompTox dashboard
Related literature
- Therapeutical properties of apigenin: a review on the experimental evidence and basic mechanisms · 2023
- Different mechanisms by which apigenin improves treatment of dermatological disorders Apigenin and its dermatological applications: A comprehensive review. · 2022
- Phytochemistry And Pharmacological Aspects Of Apigenin: A Review · 2022
- Apigenin enhances viability of random skin flaps by activating autophagy · 2021
- Apigenin as an anticancer agent. · 2020
Linked databases 15
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese