Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate.
How much products actually contain
No product states its amount yet.
Of the products containing it, 17 list it before the 1% line and 4 after it (usually 1% or less).
Products using this ingredient
12 of 20 confirmed · likeliest to carry enough first · See all 20
ColourPopColourPop Vanilla Cake
ColourPopColourPop Eevee
ColourPopColourPop Buttery Pancakes
ColourPopColourPop Caramel Latte
ColourPopColourPop Cherry Glaze
ColourPopColourPop Espeon
ColourPopColourPop Mango Sorbet
ColourPopColourPop Peach Mochi
ColourPopColourPop Shine. Shimmer. Repeat.
ColourPopColourPop Strawberry Milk
ColourPopColourPop Sugar Lips
ColourPopColourPop Umbreon
Definition
US FDA substance register · UNII Z0H242BBR1 · registered name Aspartame · single chemical substance
Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. It has a role as a micronutrient, a xenobiotic, a sweetening agent, a nutraceutical, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an apoptosis inhibitor and an environmental contaminant. It is a methyl ester, a carboxylic acid and a dipeptide. It is functionally related to a L-aspartic acid and a methyl L-phenylalaninate. It is a tautomer of an aspartame zwitterion.
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name アスパルテーム: 本品は、アスパラギン酸(*)とフェニルアラニン(*)からなるジペプチドであり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 22839-47-0
- EC No.EU chemical inventory number
- 245-261-3
- DTXSIDUS EPA chemical ID
- DTXSID0020107
- DTXCIDUS EPA compound ID
- DTXCID20107
- IUPAC
- Methyl L-alpha-aspartyl-L-phenylalaninate
- Molecular formula
- C14H18N2O5
- Molecular weight
- 294.307 g/mol
Measured properties
- Appearance
- CBI · White, odourless, crystalline powder having a sweet taste. Approximately 200 times as sweet as sucrose
- Odour
- Odorless
- Melting point
- about 190 and 245-247 · 246.5 °C
- Solubility
- The solubility of aspartame in water is dependent on pH and temperature, the maximum solubility is reached at pH 2.2 (20 mg/mL at 25 °C) and the minimum solubility at pH 5.2 (pHi) is 13.5 mg/mL at 25 °C. · Slightly soluble in water and in ethanol
- Stability
- Aspartame is stable in dry conditions. In the presence of moisture, hydrolysis occurs to form the degradation products L-aspartyl-L-phenylalanine and 3-benzyl-6-carboxymethyl-2,5-diketopiperazine with a resulting loss of sweetness. A third degradation product is also known, beta-L-aspartyl-L-phenylalanine methyl ester ... Stability in aqueous solutions has been enhanced by the addition of cyclodex · It is most stable in solution at about pH 4.3.
- pH
- Between 4,5 and 6,0 (1 in 125 solution) · 0.8% Solution in water has a pH of about 5.3.
- Dissociation constant
- 3.19 · 7.87
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient9
- Deodorizer1
Source: US EPA CompTox dashboard
Related literature
- Role of Astaxanthin in Improving the Physiological and Teratolgical Changes of Aspartame in the Pregnant Albino rats and Their Fetuses · 2016
- The Possible Protective Role of Pumpkin Seed Oil in Improving Tongue Mucosal Damage Induced by Artificial Sweeteners Aspartame (Histological study) · 2025
- Viscoelastic behavior of wormlike micellar solutions formed by an aspartame-based bicephalous anionic surfactant. · 2025
- Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products · 2021
- COMPUTATIONAL ASSESSMENT OF THE PHARMACOKINETICS AND TOXICITY OF THE INTENSIVE SWEETENERS · 2021
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese