Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate.
产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中,17 款将其列在 1% 线之前,4 款列在之后(通常不超过 1%)。
含有此成分的产品
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ColourPopColourPop Vanilla Cake
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定义
美国FDA 物质登记 · UNII Z0H242BBR1 · 登记名称 Aspartame · 单一化学物质
Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. It has a role as a micronutrient, a xenobiotic, a sweetening agent, a nutraceutical, an EC 3.1.3.1 (alkaline phosphatase) inhibitor, an apoptosis inhibitor and an environmental contaminant. It is a methyl ester, a carboxylic acid and a dipeptide. It is functionally related to a L-aspartic acid and a methyl L-phenylalaninate. It is a tautomer of an aspartame zwitterion.
来源: PubChem
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 アスパルテーム: 本品は、アスパラギン酸(*)とフェニルアラニン(*)からなるジペプチドであり、次の化学式で表される。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 22839-47-0
- EC No.欧盟化学品目录编号
- 245-261-3
- DTXSID美国EPA化学品编号
- DTXSID0020107
- DTXCID美国EPA化合物编号
- DTXCID20107
- IUPAC
- Methyl L-alpha-aspartyl-L-phenylalaninate
- 分子式
- C14H18N2O5
- 分子量
- 294.307 g/mol
实测物性
- 性状
- CBI · White, odourless, crystalline powder having a sweet taste. Approximately 200 times as sweet as sucrose
- 气味
- Odorless
- 熔点
- about 190 and 245-247 · 246.5 °C
- 溶解性
- The solubility of aspartame in water is dependent on pH and temperature, the maximum solubility is reached at pH 2.2 (20 mg/mL at 25 °C) and the minimum solubility at pH 5.2 (pHi) is 13.5 mg/mL at 25 °C. · Slightly soluble in water and in ethanol
- 稳定性
- Aspartame is stable in dry conditions. In the presence of moisture, hydrolysis occurs to form the degradation products L-aspartyl-L-phenylalanine and 3-benzyl-6-carboxymethyl-2,5-diketopiperazine with a resulting loss of sweetness. A third degradation product is also known, beta-L-aspartyl-L-phenylalanine methyl ester ... Stability in aqueous solutions has been enhanced by the addition of cyclodex · It is most stable in solution at about pH 4.3.
- pH
- Between 4,5 and 6,0 (1 in 125 solution) · 0.8% Solution in water has a pH of about 5.3.
- 解离常数
- 3.19 · 7.87
这是对物质本身测得的数值,并非原料商品的规格。
来源: PubChem
产品实际使用的用途
这是向美国 EPA 申报含该成分的 10 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Flavouring and nutrient9
- Deodorizer1
来源: 美国EPA CompTox
相关文献
- Role of Astaxanthin in Improving the Physiological and Teratolgical Changes of Aspartame in the Pregnant Albino rats and Their Fetuses · 2016
- The Possible Protective Role of Pumpkin Seed Oil in Improving Tongue Mucosal Damage Induced by Artificial Sweeteners Aspartame (Histological study) · 2025
- Viscoelastic behavior of wormlike micellar solutions formed by an aspartame-based bicephalous anionic surfactant. · 2025
- Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products · 2021
- COMPUTATIONAL ASSESSMENT OF THE PHARMACOKINETICS AND TOXICITY OF THE INTENSIVE SWEETENERS · 2021