Definition
US FDA substance register · UNII 23DG89Z6G0 · registered name BASIC RED 1:1 · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 3068-39-1
- EC No.EU chemical inventory number
- 221-326-1
- DTXSIDUS EPA chemical ID
- DTXSID80883732
- DTXCIDUS EPA compound ID
- DTXCID701023228
- IUPAC
- 3,6-Bis(ethylamino)-9-[2-(methoxycarbonyl)phenyl]-2,7-dimethylxanthen-10-ium chloride
- Molecular formula
- C27H29ClN2O3
- Molecular weight
- 464.99 g/mol
Measured properties
- Appearance
- solid
- Melting/freezing point
- 305.87 ℃(est.)
- Molecular weight
- 464.98
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye2
- Pigment2
- Solvent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: JMAFF, 12 Nousan, Notification No 8147 2000 including the most recent partial revisions according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 2015 according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) 2008 including most recent amendments according to EPA OPPTS 870.2500 (Acute Dermal Irritation) 1998 according to - Low to Moderate Frequency of Sensitization
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 2010 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) 2008 including most recent amendments according to EPA OPPTS 870.2600 (Skin Sensitisation) 2003 - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Method according to the Federal Register 38 No. 187 s 1500.42 (eye) 1973 according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Linked databases 10
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata