Ingredient Dictionary

BASIC VIOLET 3

Gentian Violet can cause cancer according to an independent committee of scientific and health experts.

Definition

Gentian Violet can cause cancer according to an independent committee of scientific and health experts.

Source: PubChem

US FDA substance register · UNII J4Z741D6O5 · registered name Gentian violet · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Dyes hairHAIR DYEING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance · priority-management substance

Source: Korea toxic substances GHS register (NIER)

Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics

Source: Health Canada Cosmetic Ingredient Hotlist

Restriction II/380 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

Reviewed by CIR: Final Report on the Safety Assessment of Basic Violet 1, Basic Violet 3 and Basic Violet 4

Source: US Cosmetic Ingredient Review (CIR)

CIR reviewed this ingredient and flagged its status as: Insufficient data ingredients with no uses reported to FDA's Voluntary Cosmetic Registration Program (VCRP) (insufficient data or use not supported — CIR's own classification, not a full safety-as-used conclusion).

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name 塩化メチルロザニリン: 本品は、次の化学式で表される頭髪用染料である。

Source: JCIA labelling names (Japan)

JCIA labelling name 塩基性紫３: 本品は、次の化学式で表される４級アンモニウム塩である。

Source: JCIA labelling names (Japan)

Names & identifiers

BASIC VIOLET 3INCI염기성자색3호Korean label name (MFDS standard)Methanaminium, N-[4-[bis[4-(dimethylamino)phenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chlorideSynonym塩化メチルロザニリンJapanese labelling name塩基性紫３Japanese labelling name

CAS No.chemical registry number: 548-62-9
EC No.EU chemical inventory number: 208-953-6
DTXSIDUS EPA chemical ID: DTXSID5020653
DTXCIDUS EPA compound ID: DTXCID50653

IUPAC: 4-{Bis[4-(dimethylamino)phenyl]methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium chloride
Molecular formula: C25H30ClN3
Molecular weight: 407.99 g/mol

Measured properties

Appearance: Hexamethyl-p-rosaniline chloride is a green to dark green powder. (NTP, 1992) · Green powder, insoluble in water, [CAMEO]
Melting point: 419 °F (Decomposes) (NTP, 1992) · 215 °C (decomposes)
Solubility: less than 1 mg/mL at 86 °F (NTP, 1992) · Very soluble in water, chloroform
Melting/freezing point: 198~250 ℃
Initial boiling point and range: 631.92 ℃
Flammability (solid, gas): not flammable
Vapour pressure: 0 ㎩ (25℃)
Water solubility: 50~100 g/ℓ (27℃, pH: 3.07)
Vapour density: 0.471 g/㎤
n-Octanol/water partition coefficient (Kow): 1.172 (log Pow, 25℃)
Auto-ignition temperature: 190 ℃
Decomposition temperature: 215 ℃

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye4

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

6 skin studies and 7 eye studies are on record.

Classed as highly irritating1Classed as low4

The studies disagree (the most common conclusion covers 20%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 13 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to
Classification not possible
Skin Sensitization · Screening
Not likely to be sensitizing
skin sensitisation · Screening · equivalent or similar to other guideline: As mentioned below
High Frequency of Sensitization
skin sensitisation · Screening · equivalent or similar to other guideline: As mentioned below
Category 6.3B (Category 3)
Skin Irritation · Read Across
Classification not possible
Skin Irritation · Screening
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Standard Eye irritation test according to
Ambiguous
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
Eye Dam. 1
Eye Irritation · Authoritative
Classification not possible
Eye Irritation · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across
Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening