What is this ingredient?

미국 FDA 물질 등록 · UNII 2HJO358I4S · 등록명 Basic Yellow 28 · 단일 화학물질

All ingredients

Ingredient Dictionary

BASIC YELLOW 28

Definition

US FDA substance register · UNII 2HJO358I4S · registered name Basic Yellow 28 · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Dyes hairHAIR DYEING

Safety & regulatory references

Banned: Argentina · ASEAN · Brazil · China · European Union · South Korea · Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex II (prohibited substances), entry 1272

Source: EU prohibited substances (Annex II)

Restriction II/1272 · Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

BASIC YELLOW 28INCI염기성황색28호Korean label name (MFDS standard)3H-Indolium, 2-[[(4-methoxyphenyl)methylhydrazono]methyl]-1,3,3-trimethyl-, methyl sulfateSynonym

CAS No.chemical registry number: 54060-92-3
EC No.EU chemical inventory number: 258-946-7
DTXSIDUS EPA chemical ID: DTXSID20879816
DTXCIDUS EPA compound ID: DTXCID001017816

IUPAC: 2-{[2-(4-Methoxyphenyl)-2-methylhydrazinylidene]methyl}-1,3,3-trimethyl-3H-indol-1-ium methyl sulfate
Molecular formula: C21H27N3O5S
Molecular weight: 433.52 g/mol

Measured properties

Appearance: solid
Molecular weight: 433.52

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Dye1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low3

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation)
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to