BENZETHONIUM CHLORIDE

Benzethonium chloride is a (synthetic) quaternary ammonium salt that is benzyldimethylamine in which the nitrogen is quaternised by a 2-{2-[p-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy}ethyl group, with chloride as the counter-ion. An antiseptic and disinfectant, it is active against a broad spectrum of bacteria, fungi, moulds and viruses. It has a role as an antiviral agent, an antibacterial agent, an antifungal agent, an antiseptic drug and a disinfectant. It is a chloride salt, a quaternary ammonium salt and an aromatic ether.

来源: PubChem

美国FDA 物质登记 · UNII PH41D05744 · 登记名称 Benzethonium Chloride · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Benzethonium Chloride is the quaternary ammonium salt that conforms to the formula:

准用防腐剂

英国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 日本化妆品标准 · 台湾FDA 化妆品成分 · 英国化妆品法规

阿根廷 · 巴西

• Maximum concentration permitted at final product : 0.1%
• Other limitations and requirements : Prohibited in products not rinsed for oral hygiene.

东盟

• Maximum authorised concentration in the finished cosmetic product : 0.1%
• Other limitations and requirements : (a) Rinse-off products (b) Leave on products other than for oral care use.

加拿大

• Conditions of Use by product type : (a) Not permitted in products to be applied to mucous membranes. (b) Leave-on products (c) Rinse-off products
• Maximum Concentration Permitted : b) 0.2% c) 0.3%

台湾

• 倘前述三國家地區政府管理有差異時，則採其中限量規定方式最安全者。
• ※ 本表所稱之口腔製劑，包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
• 用途 : 防腐
• 最大配合量 : (a) 立即沖洗產品：0.1%
• (b) 非立即沖洗產品(口腔製劑除外)：0.1%

日本

• 每100g最大配合量 (Cosmetics not used for mucosa and to be washed away) : 0.50 g
• 每100g最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 0.20 g

中国

• 最大配合量 : 0.1%

韩国

• 最大配合量 : 0.10%

欧盟

• Product Type, body parts : a) Rinse-off products b) Leave-on products other than oral products
• Maximum concentration in ready for use preparation : 0.1%

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

欧盟化妆品法规 附录V（准用防腐剂） 第53项 · 最高浓度 0.1% · 适用 a) Rinse-off products b) Leave-on products other than oral products

来源: 欧盟准用防腐剂（附录V）

Restriction V/53

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2004/2005

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of Benzethonium Chloride and Methylbenzethonium Chloride

来源: 美国CIR 安全性评估