Definition
Benzophenone-2 is a benzophenone derivative that conforms to the formula:
US FDA substance register · UNII PRR8K3H9VN · registered name BENZOPHENONE-2 · single chemical substance
Cosmetic roles
Safety & regulatory references
Japan
- Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 10 g
- Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 10 g
- Maximum amount per 100 g (Cosmetics that may be used for mucosa) : 0.050
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003
Reviewed by CIR: Addendum to the Final Report on the Safety Assessment of Benzophenones-1, -3, -4, -5, .-9, and -11 to Include Benzophenones-2, -6, and -8 (JACT 2(5): 35-77, 1983.)
Reviewed by CIR: Final Report: Amended Safety Assessment of Benzophenones as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name オキシベンゾン－２: 本品は、ベンゾフェノンの誘導体であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 131-55-5
- EC No.EU chemical inventory number
- 205-028-9
- DTXSIDUS EPA chemical ID
- DTXSID5041306
- DTXCIDUS EPA compound ID
- DTXCID3021306
- IUPAC
- Bis(2,4-dihydroxyphenyl)methanone
- Molecular formula
- C13H10O5
- Molecular weight
- 246.218 g/mol
Measured properties
- Appearance
- Yellow needles · Light yellow powder
- Boiling point
- 491 °C
- Melting point
- 198.8 °C
- Solubility
- In water, 8,821 mg/L at 24.99 °C · In water, <1 g/100 mL at 30 °C
- Density
- 1.21 g/cu cm at 25 °C
- Stability
- Stable under recommended storage conditions.
- Molecular weight
- 246.23
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 22 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- UV stabilizer18
- Fragrance2
- Deodorizer2
Source: US EPA CompTox dashboard
Related literature
- The effect of dermal benzophenone-2 administration on immune system activity, hypothalamic-pituitary-thyroid axis activity and hematological parameters in male Wistar rats. · 2018
- Decoding DNA Interactions of Cosmetic Compounds: A Multi-Scale In-Silico Approach · 2026
- Ecotoxicological assessment of a sunscreen-derived pollutant, benzophenone-2, on freshwater fish (Labeo rohita) · 2025
- Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers · 2019
- Combined effect of Benzophenone‐2 and ultraviolet radiation promote photogenotoxicity and photocytotoxicity in human keratinocytes · 2018
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata