オキシベンゾン－３

Oxybenzone is a hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively. It has a role as a xenobiotic, a dermatologic drug, a protective agent, an ultraviolet filter and an environmental contaminant. It is a hydroxybenzophenone and a monomethoxybenzene.

出典: PubChem

米国FDA 物質登録 · UNII 95OOS7VE0Y · 登録名 OXYBENZONE · 単一の化学物質

出典: 米国FDA 物質識別番号（UNII）

Benzophenone-3 is a benzophenone derivative that conforms to the formula:

許可された紫外線吸収剤

イギリス

出典: ASEAN 化粧品指令 · EU 化粧品規則 · 台湾FDA 化粧品成分 · 英国 化粧品規則

アルゼンチン · ブラジル

• Maximum concentration permitted at final product : 10%
• Other limitations and requirements : For concentrations greater than 0.5%, include a warning on the label: "contains Benzophenone-3"

ASEAN

• Maximum authorised concentration in the finished cosmetic product : 6%
• Conditions of use and warning which must be printed on the labels : Contains oxybenzone (Not required if concentration is 0.5% or less and when it is used only for product protection purposes)

カナダ

• Maximum Concentration Permitted : ≤ 6%

台湾

• 用途 : 防曬劑
• 最大配合量 : 6% (作為保護劑用途，限量 ≤0.5%)
• 6%

アメリカ合衆国

• Specific Limitations and Comments : Use of the term "sunscreen" or similar sun protection wording in a product's labeling generally causes the product to be subject to regulation as a drug or a drug/cosmetic, depending on the claims. However, sunscreen ingredients may also be used in some cosmetic products to protect the products’ color. The labelling must also state why the sunscreen ingredient is used, for example, "Contains a sunscreen to protect product color." If this explanation isn’t present, the product may be subject to regulation as a drug (21 CFR 700.35). For more information on sunscreens, refer to Tanning Products

日本

• 100gあたりの最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 5.0 g
• 100gあたりの最大配合量 (Cosmetics that may be used for mucosa) : 5.0 g

中国

• 最大配合量 : 10%

韓国

• 最大配合量 : 5%

欧州連合

• Product Type, body parts : (a) Face products, hand products, and lip products, excluding propellant and pump spray products (b) Body products, including propellant and pump spray products (c) Other products
• Maximum concentration in ready for use preparation : (a) 6% (b) 2,2% (c) 0,5% Footnote 1: However, cosmetic products containing '2-Hydroxy-4-methoxy-benzophenone/Oxybenzone' and complying with the restrictions set out in Regulation (EC) No 1223/2009 as applicable on 27 July 2022 may be placed on the Union market until 28 January 2023 and be made available on the Union market until 28 July 2023.
• Other : (a) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 5,5 %. (b) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 1,7 %.
• Wording of conditions of use and warnings : For (a) and (b): Contains Benzophenone-3 (*) Footnote (*): Not required if concentration is 0,5 % or less and when it is used only for product protection purposes.

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報（環境公団）

EU化粧品規則 附属書VI（許可紫外線吸収剤） 第4項 · 最大濃度 a) 6% b) 2,2% c) 0,5% Footnote 1: However, cosmetic products containing '2-Hydroxy-4-methoxy-benzophenone/Oxybenzone' and complying with the restrictions set out in Regulation (EC) No 1223/2009 as applicable on 27 July 2022 may be placed on the Union market until 28 January 2023 and be made available on the Union market until 28 July 2023. · 適用 a) Face products, hand products, and lip products, excluding propellant and pump spray products b) Body products, including propellant and pump spray products c) Other products

出典: EU 許可紫外線吸収剤（附属書VI）

Restriction VI/4 · SCCS opinion: Opinion on Benzophenone-3; OPINION on Benzophenone-3

出典: EU CosIng 成分リスト

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report: Amended Safety Assessment of Benzophenones as Used in Cosmetics

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of Benzophenones-1, -3, -4, -5, -9, and -11

出典: 米国CIR 安全性評価