BENZOPHENONE-3

Oxybenzone is a hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively. It has a role as a xenobiotic, a dermatologic drug, a protective agent, an ultraviolet filter and an environmental contaminant. It is a hydroxybenzophenone and a monomethoxybenzene.

来源: PubChem

美国FDA 物质登记 · UNII 95OOS7VE0Y · 登记名称 OXYBENZONE · 单一化学物质

来源: 美国FDA 物质识别码（UNII）

Benzophenone-3 is a benzophenone derivative that conforms to the formula:

准用防晒剂

英国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 台湾FDA 化妆品成分 · 英国化妆品法规

阿根廷 · 巴西

• Maximum concentration permitted at final product : 10%
• Other limitations and requirements : For concentrations greater than 0.5%, include a warning on the label: "contains Benzophenone-3"

东盟

• Maximum authorised concentration in the finished cosmetic product : 6%
• Conditions of use and warning which must be printed on the labels : Contains oxybenzone (Not required if concentration is 0.5% or less and when it is used only for product protection purposes)

加拿大

• Maximum Concentration Permitted : ≤ 6%

台湾

• 用途 : 防曬劑
• 最大配合量 : 6% (作為保護劑用途，限量 ≤0.5%)
• 6%

美国

• Specific Limitations and Comments : Use of the term "sunscreen" or similar sun protection wording in a product's labeling generally causes the product to be subject to regulation as a drug or a drug/cosmetic, depending on the claims. However, sunscreen ingredients may also be used in some cosmetic products to protect the products’ color. The labelling must also state why the sunscreen ingredient is used, for example, "Contains a sunscreen to protect product color." If this explanation isn’t present, the product may be subject to regulation as a drug (21 CFR 700.35). For more information on sunscreens, refer to Tanning Products

日本

• 每100g最大配合量 (Cosmetics not used for mucosa and not to be washed away) : 5.0 g
• 每100g最大配合量 (Cosmetics that may be used for mucosa) : 5.0 g

中国

• 最大配合量 : 10%

韩国

• 最大配合量 : 5%

欧盟

• Product Type, body parts : (a) Face products, hand products, and lip products, excluding propellant and pump spray products (b) Body products, including propellant and pump spray products (c) Other products
• Maximum concentration in ready for use preparation : (a) 6% (b) 2,2% (c) 0,5% Footnote 1: However, cosmetic products containing '2-Hydroxy-4-methoxy-benzophenone/Oxybenzone' and complying with the restrictions set out in Regulation (EC) No 1223/2009 as applicable on 27 July 2022 may be placed on the Union market until 28 January 2023 and be made available on the Union market until 28 July 2023.
• Other : (a) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 5,5 %. (b) If used at 0,5 % to protect product formulation, the levels used as UV filter must not exceed 1,7 %.
• Wording of conditions of use and warnings : For (a) and (b): Contains Benzophenone-3 (*) Footnote (*): Not required if concentration is 0,5 % or less and when it is used only for product protection purposes.

未列入韩国有毒物质 GHS 分类 · 现有化学物质

来源: 韩国有毒物质 GHS 信息（环境公团）

欧盟化妆品法规 附录VI（准用防晒剂） 第4项 · 最高浓度 a) 6% b) 2,2% c) 0,5% Footnote 1: However, cosmetic products containing '2-Hydroxy-4-methoxy-benzophenone/Oxybenzone' and complying with the restrictions set out in Regulation (EC) No 1223/2009 as applicable on 27 July 2022 may be placed on the Union market until 28 January 2023 and be made available on the Union market until 28 July 2023. · 适用 a) Face products, hand products, and lip products, excluding propellant and pump spray products b) Body products, including propellant and pump spray products c) Other products

来源: 欧盟准用防晒剂（附录VI）

Restriction VI/4 · SCCS opinion: Opinion on Benzophenone-3; OPINION on Benzophenone-3

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report: Amended Safety Assessment of Benzophenones as Used in Cosmetics

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of Benzophenones-1, -3, -4, -5, -9, and -11

来源: 美国CIR 安全性评估