Sulisobenzone is a member of benzophenones.
- Korean limit
- 5%
How much products actually contain
No product states its amount yet.
Of the products containing it, 21 list it before the 1% line and 39 after it (usually 1% or less).
Products using this ingredient
12 of 59 confirmed · likeliest to carry enough first · See all 59
MoroccanoilMoroccanoil Root Boost
Not Your Mother'sNot Your Mother's Fragrance & Protein Free Activating Mousse
American CrewAmerican Crew GROOMING SPRAY
OuidadOuidad VitalCurl®+ Soft Defining Mousse
R+CoR+Co SKYLINE Dry Shampoo Powder
MoroccanoilMoroccanoil Luminous Hairspray Extra Strong
OUAIOUAI Body Cleanser Dean Street
OUAIOUAI Body Cleanser Melrose Place
OUAIOUAI Body Cleanser Melrose Place - Travel
Baxter of CaliforniaBaxter of California HARD WATER POMADE
IGK HairIGK Hair Direct Flight Dry Shampoo
IGK HairIGK Hair Direct Flight Travel
Definition
Sulisobenzone is a member of benzophenones.
Source: PubChem
US FDA substance register · UNII 1W6L629B4K · registered name SULISOBENZONE · single chemical substance
Benzophenone-4 is a benzophenone derivative that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Restricted
- China
- Allowed UV filter
- United Kingdom
Source: MFDS (Korea) cosmetic regulatory information · EU Cosmetics Regulation · Taiwan FDA cosmetic ingredients · UK cosmetics regulations (OPSS)
Argentina · Brazil
- Maximum concentration permitted at final product : 10% (expresado como ácido)
ASEAN
- Maximum authorised concentration in the finished cosmetic product : 5% (as acid)
Canada
- Maximum Concentration Permitted : ≤ 10%
Taiwan
- 5%
United States
- Specific Limitations and Comments : Use of the term "sunscreen" or similar sun protection wording in a product's labeling generally causes the product to be subject to regulation as a drug or a drug/cosmetic, depending on the claims. However, sunscreen ingredients may also be used in some cosmetic products to protect the products’ color. The labelling must also state why the sunscreen ingredient is used, for example, "Contains a sunscreen to protect product color." If this explanation isn’t present, the product may be subject to regulation as a drug (21 CFR 700.35). For more information on sunscreens, refer to Tanning Products
Japan
- Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 10 g
- Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 10 g
- Maximum amount per 100 g (Cosmetics that may be used for mucosa) : 0.10 g
South Korea
- Maximum concentration : 5%
European Union
- Maximum concentration in ready for use preparation : 5%(as acid)
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction VI/22
Source: EU CosIng ingredient list
Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2002/2003
Reviewed by CIR: Final Report on the Safety Assessment of Benzophenones-1, -3, -4, -5, -9, and -11
Reviewed by CIR: Final Report: Amended Safety Assessment of Benzophenones as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name オキシベンゾン－４: 本品は、ベンゾフェノンの誘導体であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 4065-45-6
- EC No.EU chemical inventory number
- 223-772-2
- DTXSIDUS EPA chemical ID
- DTXSID2042436
- DTXCIDUS EPA compound ID
- DTXCID0022436
- IUPAC
- 5-Benzoyl-4-hydroxy-2-methoxybenzene-1-sulfonic acid
- Molecular formula
- C14H12O6S
- Molecular weight
- 308.3 g/mol
Measured properties
- Appearance
- Light tan solid, [Merck Index] · Light-tan powder
- Melting point
- 145 · 145 °C
- Solubility
- 10 microgram/mL · In water, 2.5X10+5 mg/L at 25 °C
- Stability
- Stable under recommended storage conditions.
- Dissociation constant
- pKa1 = -2.4 (sulfonic acid), pKa2 = 7.6 (hydroxyl)
- Molecular weight
- 308.31
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 87 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- UV stabilizer85
- Fragrance1
- Antioxidant1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) according to EPA OPP 81-6 (Skin Sensitisation)
Source: US EPA CompTox dashboard
Related literature
- Hydroxypropyl Methylcellulose Bioadhesive Hydrogels for Topical Application and Sustained Drug Release: The Effect of Polyvinylpyrrolidone on the Physicomechanical Properties of Hydrogel · 2023
- Building confidence in PBK model predictions in the absence of human kinetic data: Benzophenone-4 case study_suppl1 · 2025
- Building confidence in PBK model predictions in the absence of human kinetic data: Benzophenone-4 case study. · 2025
- Making safety decisions for a sunscreen active ingredient using next-generation risk assessment: Benzophenone-4 case study. · 2025
- Modification of Carbon Paste Electrode with MWCNTs and Benzethonium chloride and its Application as a Novel Sensor for Determination of Benzophenone-4 in Cosmetic Preparations · 2020
Linked databases 25
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU SCCS safety opinions
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3 4
- PubChem 2
- Taiwan FDA cosmetic ingredients
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese