Benzotriazole is the simplest member of the class of benzotriazoles that consists of a benzene nucleus fused to a 1H-1,2,3-triazole ring.
定义
Benzotriazole is the simplest member of the class of benzotriazoles that consists of a benzene nucleus fused to a 1H-1,2,3-triazole ring. It has a role as a xenobiotic and an environmental contaminant.
来源: PubChem
美国FDA 物质登记 · UNII 86110UXM5Y · 登记名称 Benzotriazole · 单一化学物质
化妆品中的作用
安全与法规参考
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Opinion concerning Azole Antimycotic Resistance
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 95-14-7
- EC No.欧盟化学品目录编号
- 202-394-1
- DTXSID美国EPA化学品编号
- DTXSID6020147
- DTXCID美国EPA化合物编号
- DTXCID00147
- IUPAC
- 1H-1,2,3-Benzotriazole
- 分子式
- C6H5N3
- 分子量
- 119.127 g/mol
实测物性
- 性状
- 固体
- 熔点/凝固点
- 98.5 ℃
- 初沸点和沸程
- 204 ℃(@ 2 kPa)
- 闪点
- 190~195 ℃ (o.c.)
- 易燃性（固体、气体）
- 可燃
- 蒸气压
- 5 ㎩ (@ 20 ℃)
- 溶解度
- 19800 ㎎/ℓ (@ 25 ℃)
- 蒸气密度
- 4.11
- 比重
- 1.4 (@ 20 ℃)
- 正辛醇/水分配系数（Kow）
- 1.44
- 自燃温度
- 210 ℃
- 分子量
- 119.13
这是对物质本身测得的数值。韩国安全保健公团（KOSHA）的资料仅供编写和审核安全数据表参考，并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 46 款产品的用途。其中包括化妆品以外的产品，排在前几行的即为该成分的主要用途。
- Preservative17
- Corrosion inhibitor9
- UV stabilizer5
- Lubricating agent3
- Intermediate2
- Stabilizing agent2
- Plating agent1
- Defoamer1
其余用途 6 项
- Anti-freeze agent1
- Pharmaceutical (EPA)1
- Processing aids not otherwise specified1
- Anti-scaling agent1
- Biocide1
- Cleaning agent1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 2 项。
试验结论基本一致（100%）。 这是对原料本身的试验记录，与成品中所含浓度下的刺激性不同。
查看全部 6 项试验
- Not classified
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Category 2
Eye Irritation · Screening
来源: 美国EPA CompTox
相关文献
- Benzotriazole UV stabilizers disrupt epidermal growth factor receptor signaling in human cells. · 2024
- Tissue-Specific Accumulation, Biotransformation, and Physiologically Based Toxicokinetic Modeling of Benzotriazole Ultraviolet Stabilizers in Zebrafish (Danio rerio). · 2021
- Occurrence of benzotriazole UV stabilizers in coastal fishes. · 2020
- Occurrence, distribution, and health risk assessment of 20 personal care products in indoor and outdoor swimming pools. · 2020
- Synthesis and Application of UV Absorber of Benzotriazole Compound Containing a Disulfide Bond · 2014